Département de chimie moléculaire

Assessment of new 2'-O-acetalester protecting groups for regular RNA synthesis and original 2'-modified proRNA, Martin, A. R., Lavergne Thomas, Vasseur J. J., and Debart F. , Bioorganic & Medicinal Chemistry Letters, Volume 19, Number 15, p.4046-9, (2009)

A base-labile group for 2'-OH protection of ribonucleosides: a major challenge for RNA synthesis, Lavergne, Thomas, Bertrand J. R., Vasseur J. J., and Debart F. , Chemistry, Volume 14, Number 30, p.9135-8, (2008)

The biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structure, Baraguey, C., Lescrinier E., Lavergne Thomas, Debart F., Herdewijn P., and Vasseur J. J. , Organic & Biomolecular Chemistry, Volume 11, Number 16, p.2638-47, (2013)

Chemical synthesis of RNA with base-labile 2'-o-(pivaloyloxymethyl)-protected ribonucleoside phosphoramidites, Lavergne, Thomas, Janin M., Dupouy C., Vasseur J. J., and Debart F. , Curr Protoc Nucleic Acid Chem, Volume Chapter 3, p.Unit3 19, (2010)

Efficient solid-phase chemical synthesis of 5'-triphosphates of DNA, RNA, and their analogues, Zlatev, I., Lavergne Thomas, Debart F., Vasseur J. J., Manoharan M., and Morvan F. , Organic Letters, Volume 12, Number 10, p.2190-3, (2010)

Synthesis and preliminary evaluation of pro-RNA 2'-O-masked with biolabile pivaloyloxymethyl groups in an RNA interference assay, Lavergne, Thomas, Baraguey C., Dupouy C., Parey N., Wuensche W., Sczakiel G., Vasseur J. J., and Debart F. , Journal of Organic Chemistry, Volume 76, Number 14, p.5719-31, (2011)