91 resultats trouvés
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] Filtres: Auteur est Eric Defrancq [Clear All Filters]
Novel Synthesis of IMC-48 and Affinity Evaluation with Different i-Motif DNA Sequences,
, Molecules, 01/2023, Volume 28, (2023)
Assessment of presumed small-molecule ligands of telomeric i-DNA by BioLayer Interferometry (BLI),
, Chem. Commun., 04/2022, Volume 58, p.5116-5119, (2022)
Conformational transition in SPR experiments: impact of spacer length, immobilization mode and aptamer density on signal sign and amplitude,
, Analyst, 08/2022, Volume 147, p.4197-4205, (2022)
Photo-induced telomeric DNA damage in human cancer cells,
, RSC Chem. Biol., 10/2022, Volume 3, p.1375, (2022)
Photo-oxidizing Ruthenium(II) Complexes with Enhanced Visible Light Absorption and G-quadruplex DNA Binding Abilities,
, Chemistry – A European Journal, 08/2022, Volume 28, (2022)
Constrained G4 structures unveil topology specificity of known and new G4 binding proteins,
, Scientific Reports, 06/2021, Volume 11, p.13469, (2021)
Negative SPR Signals during Low Molecular Weight Analyte Recognition,
, Analytical Chemistry, 02/2021, Volume 93, Issue 8, p.4134–4140, (2021)
Recent progress in the design of G-quadruplex based electrochemical aptasensors,
, Current Opinion in Electrochemistry, 07/2021, p.100812, (2021)
Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands,
, eLife, 06/2021, Volume 10, p.e65184, (2021)
Access to a stabilized i-motif DNA structure through four successive ligation reactions on a cyclopeptide scaffold,
, Org. Biomol. Chem., 07/2020, Volume 18, p.6394-6406, (2020)
Direct Detection of Low-Molecular-Weight Compounds in 2D and 3D Aptasensors by Biolayer Interferometry,
, ACS Sensors, 08/2020, Volume 5, Issue 8, p.2326 – 2330, (2020)
Flexible RuII Schiff Base Complexes: G-Quadruplex DNA Binding and Photo-Induced Cancer Cell Death,
, Chemistry – A European Journal, Volume 26, p.13849-13860, (2020)
Post-synthetic transamination at position N4 of cytosine in oligonucleotides assembled with routinely used phosphoramidites,
, Org. Biomol. Chem., Volume 18, p.9632-9638, (2020)
Post-synthetic transamination at position N4 of cytosine in oligonucleotides assembled with routinely used phosphoramidites,
, Org. Biomol. Chem., 11/2020, p.-, (2020)
Redox-Active Bis-Cyclometalated Iridium(III) Complex as a DNA Photo-Cleaving Agent,
, Inorganic Chemistry, 01/2020, Volume 59, p.2426-2433, (2020)
Surface plasmon resonance study of the interaction of N-methyl mesoporphyrin IX with G-quadruplex DNA,
, Phys. Chem. Chem. Phys., 02/2020, Volume 22, p.4158-4164, (2020)
Influence of Aptamer Surface Coverage on Small Target Recognition: A SPR and QCM-D Comparative Study,
, J. Phys. Chem. C, Volume 123, p.13561–13568, (2019)
Photodetection of DNA mismatches by dissymmetric Ru(ii) acridine based complexes,
, Inorg. Chem. Front., p.2260-2270, (2019)
Scaffold stabilization of a G-triplex and study of its interactions with G-quadruplex targeting ligands.,
, Org. Biomol. Chem., Volume 17, p.8726–8736, (2019)
Scaffold stabilization of a G-triplex and study of its interactions with G-quadruplex targeting ligands,
, Org. Biomol. Chem., Volume 17, p.8726-8736, (2019)
Targeting G-Rich DNA Structures with Photoreactive Bis-Cyclometallated Iridium(III) Complexes,
, Chemistry – A European Journal, Volume 25, p.12730-12739, (2019)
Efficient Buchwald-Hartwig-Migita Cross-Coupling for DNA Thio-glycoconjugation.,
, Chem. - A Eur. J., Volume 24, Number 8, p.1795–1800, (2018)
Impact of Conformational Transitions on SPR Signals-Theoretical Treatment and Application in Small Analytes/Aptamer Recognition.,
, J. Phys. Chem. C, Volume 122, Number 37, p.21521–21530, (2018)
Influence of the SPR Experimental Conditions on the G-Quadruplex DNA Recognition by Porphyrin Derivatives.,
, Langmuir, Volume 34, Number 43, p.13057–13064, (2018)
Synthesis and photophysical studies of a multivalent photoreactive RuII-calix[4]arene complex bearing RGD-containing cyclopentapeptides.,
, Beilstein J. Org. Chem., Volume 14, p.1758–1768, (2018)
Towards the Development of Photo-Reactive Ruthenium(II) Complexes Targeting Telomeric G-Quadruplex DNA.,
, Chem. - A Eur. J., Volume 24, Number 72, p.19216–19227, (2018)
New Ruthenium-Based Probes for Selective G-Quadruplex Targeting.,
, Chem. - A Eur. J., Volume 23, Number 49, p.11872–11880, (2017)
An oxime-based glycocluster microarray.,
, Org. Biomol. Chem., Volume 15, Number 24, p.5135–5139, (2017)
Palladium-Mediated Labeling of Nucleic Acids.,
, ChemBioChem, Volume 18, Number 5, p.426–431, (2017)
The pKa value of the proximal water molecule trans to a high-valent MnV=O porphyrin: towards the control of reactivity by pH.,
, Dalt. Trans., Volume 46, Number 36, p.12088–12094, (2017)
Template-mediated stabilization of a DNA G-quadruplex formed in the HIV-1 promoter and comparative binding studies.,
, Chem. - A Eur. J., Volume 23, Number 23, p.5602–5613, (2017)
Binding of metalloporphyrins to G-quadruplex DNA: The role of the central metal.,
, Inorganica Chim. Acta, Volume 452, p.98–103, (2016)
Efficient Inhibition of Telomerase by Nickel-Salophen Complexes.,
, ChemMedChem, Volume 11, Number 11, p.1133–1136, (2016)
Highly DNA-Photoreactive Ruthenium 1,4,5,8-Tetraazaphenanthrene Complex Conjugated to the TAT Peptide: Efficient Vectorization inside HeLa Cells without Phototoxicity - The Importance of Cellular Distribution.,
, Eur. J. Inorg. Chem., Volume 2016, Number 18, p.2902–2911, (2016)
Highly Sensitive Bisphenol-A Electrochemical Aptasensor Based on Poly(Pyrrole-Nitrilotriacetic Acid)-Aptamer Film.,
, Anal. Chem. (Washington, DC, United States), Volume 88, Number 14, p.7268–7273, (2016)
A label-free photoelectrochemical cocaine aptasensor based on an electropolymerized ruthenium-intercalator complex.,
, Electrochim. Acta, Volume 219, p.82–87, (2016)
Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties.,
, Chem. - A Eur. J., Volume 22, Number 5, p.1760–1767, (2016)
Templated Formation of Discrete RNA and DNA:RNA Hybrid G-Quadruplexes and Their Interactions with Targeting Ligands.,
, Chem. - A Eur. J., Volume 22, Number 9, p.3139–3147, (2016)
Assessment of the Full Compatibility of Copper(I)-Catalyzed Alkyne-Azide Cycloaddition and Oxime Click Reactions for bis-Labelling of Oligonucleotides.,
, ChemistryOpen, Volume 4, Number 2, p.169–173, (2015)
Cobalt(III)porphyrin to target G-quadruplex DNA.,
, Dalt. Trans., Volume 44, Number 8, p.3701–3707, (2015)
Construction of anti-parallel G-quadruplexes through sequential templated click.,
, Chem. Commun. (Cambridge, United Kingdom), Volume 51, Number 23, p.4850–4853, (2015)
Macrocyclic Host-Dye Reporter for Sensitive Sandwich-Type Fluorescent Aptamer Sensor.,
, Anal. Chem. (Washington, DC, United States), Volume 87, Number 6, p.3139–3143, (2015)
The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells.,
, JBIC, J. Biol. Inorg. Chem., Volume 20, Number 4, p.729–738, (2015)
Parameters influencing the photo-induced electron transfer from tryptophan-containing peptides to a RuII complex: a systematic study.,
, Faraday Discuss., Volume 185, p.267–284, (2015)
Sensor Based on Aptamer Folding to Detect Low-Molecular Weight Analytes.,
, Anal. Chem. (Washington, DC, United States), Volume 87, Number 15, p.7566–7574, (2015)
Interaction of Polycationic Ni(II)-Salophen Complexes with G-Quadruplex DNA.,
, Inorg. Chem., Volume 53, Number 23, p.12519–12531, (2014)
Label-free photoelectrochemical detection of double-stranded HIV DNA by means of a metallointercalator-functionalized electrogenerated polymer.,
, Chem. - A Eur. J., Volume 20, Number 47, p.15555–15560, (2014)
Specificity of light-induced covalent adduct formation between RuII oligonucleotide conjugates and target sequences for gene silencing applications.,
, Eur. J. Inorg. Chem., Volume 2014, Number 19, p.3016–3022, (2014)
Surface-immobilized DNAzyme-type biocatalysis.,
, Nanoscale, Volume 6, Number 5, p.2693–2701, (2014)
Characterization of a modified gold platform for the development of a label-free anti-thrombin aptasensor.,
, Biosens. Bioelectron., Volume 41, p.424–429, (2013)
Closer to nature: an ATP-driven bioinspired catalytic oxidation process.,
, Chem. Commun. (Cambridge, United Kingdom), Volume 49, Number 15, p.1500–1502, (2013)
Electrogenerated trisbipyridyl Ru(II)-/nitrilotriacetic-polypyrene copolymer for the easy fabrication of label-free photoelectrochemical immunosensor and aptasensor: Application to the determination of thrombin and anti-cholera toxin antibody.,
, Biosens. Bioelectron., Volume 42, p.556–562, (2013)
Evaluation of a new biocompatible poly(N-(morpholino ethyl methacrylate))-based copolymer for the delivery of ruthenium oligonucleotides, targeting HPV16 E6 oncogene.,
, J. Biomed. Nanotechnol., Volume 9, Number 8, p.1432–1440, (2013)
Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications.,
, Chem. Soc. Rev., Volume 42, Number 11, p.4557–4573, (2013)
Label-free impedimetric thrombin sensor based on poly(pyrrole-nitrilotriacetic acid)-aptamer film,
, Biosensors and Bioelectronics, Volume 41, p.90 - 95, (2013)
Oligonucleotide Functionalization of Hollow Triangular Gold Silver Alloy Nanoboxes.,
, J. Phys. Chem. C, Volume 117, Number 1, p.669–676, (2013)
Optical properties and in vitro biological studies of oligonucleotide-modified quantum dots.,
, J. Nanomater., p.463951, 11 pp., (2013)
Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53.,
, Gene Ther., Volume 20, Number 4, p.435–443, (2013)
Synthesis and characterization of oligonucleotide conjugates bearing electroactive labels.,
, Bioorg. Med. Chem. Lett., Volume 23, Number 4, p.955–958, (2013)
Use of T-2 toxin-immobilized amine-activated beads as an efficient affinity purification matrix for the isolation of specific IgY.,
, J. Chromatogr. B Anal. Technol. Biomed. Life Sci., Volume 923-924, p.98–101, (2013)
What Are the Parameters Controlling Inter- vs. Intra-Strand DNA Photodamage with Ru-TAP Oligonucleotides?.,
, Eur. J. Inorg. Chem., Volume 2013, Number 2, p.208–216, (2013)
Click-click chemistry on a peptidic scaffold for easy access to tetrameric DNA structures.,
, Chem. Commun. (Cambridge, United Kingdom), Volume 48, Number 48, p.5992–5994, (2012)
Phosphorylating Reagent-Free Synthesis of 5'-Phosphate Oligonucleotides by Controlled Oxidative Degradation of Their 5'-End.,
, Org. Lett., Volume 14, Number 8, p.2030–2033, (2012)
Photocrosslinking between Peptide-Peptide or Peptide-Oligonucleotide by RuII-TAP Complexes.,
, Chem. - A Eur. J., Volume 18, Number 1, p.55–364, S355/1–S355/7, (2012)
Controlled Density Patterning of Tolylterpyridine-Tagged Oligonucleotides.,
, Langmuir, Volume 27, Number 14, p.8595–8599, (2011)
Improvement of porphyrins for G-quadruplex DNA targeting.,
, Biochimie, Volume 93, Number 8, p.1310–1317, (2011)
Methods for investigating G-quadruplex DNA/ligand interactions.,
, Chem. Soc. Rev., Volume 40, Number 11, p.5293–5307, (2011)
Plasmon-induced CD response of oligonucleotide-conjugated metal nanoparticles.,
, Chem. Commun. (Cambridge, United Kingdom), Volume 47, Number 26, p.7383–7385, (2011)
The Use of a Peptidic Scaffold for the Formation of Stable Guanine Tetrads: Control of a H-bonded Pattern in Water.,
, Chem. - A Eur. J., Volume 17, Number 21, p.5791–5795, S5791/1–S5791/21, (2011)
Versatile Introduction of Azido Moiety into Oligonucleotides through Diazo Transfer Reaction.,
, Org. Lett., Volume 13, Number 20, p.5672–5675, (2011)
Label-free femtomolar detection of target DNA by impedimetric DNA sensor based on poly(pyrrole-nitrilotriacetic acid) film.,
, Anal. Chem. (Washington, DC, United States), Volume 82, Number 3, p.1066–1072, (2010)
Metal-Complex/DNA Conjugates: A Versatile Building Block for DNA Nanoarrays.,
, Chem. - A Eur. J., Volume 16, Number 43, p.12780–12787, (2010)
Molecular engineering of biomolecules for nanobio-sciences.,
, Int. J. Nanotechnol., Volume 7, Number 4/5/6/7/8, p.738–752, (2010)
Oligonucleotide Sequential Bis-Conjugation via Click-Oxime and Click-Huisgen Procedures.,
, J. Org. Chem., Volume 75, Number 11, p.3927–3930, (2010)
Photoinduced Electron Transfer from Tryptophan to RuIITAP Complexes: The Primary Process for Photo-Cross-Linking with Oligopeptides.,
, Inorg. Chem., Volume 49, Number 23, p.10867–10874, (2010)
Photo-reactive RuII-oligonucleotide conjugates: influence of an intercalating ligand on the inter- and intra-strand photo-ligation processes.,
, Dalt. Trans., Volume 39, Number 40, p.9672–9683, (2010)
Recent developments in oligonucleotide conjugation.,
, Chem. Soc. Rev., Volume 39, Number 6, p.2054–2070, (2010)
A Rigid Dinuclear Ruthenium(II) Complex as an Efficient Photoactive Agent for Bridging Two Guanine Bases of a Duplex or Quadruplex Oligonucleotide.,
, Chem. - A Eur. J., Volume 16, Number 13, p.3951–3961, S3951/1–S3951/9, (2010)
Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies.,
, Chem. - A Eur. J., Volume 16, Number 20, p.6106–6114, S6106/1–S6106/16, (2010)
Design and synthesis of novel hybrid metal complex-DNA conjugates: Key building blocks for multimetallic linear DNA nanoarrays.,
, Org. Biomol. Chem., Volume 7, Number 13, p.2729–2737, (2009)
Efficient conjugation of oligonucleotides through aromatic oxime formation.,
, Bioorg. Med. Chem. Lett., Volume 19, Number 23, p.6534–6537, (2009)
Oligonucleotide duplexes with tethered photoreactive ruthenium(II) complexes: influence of the ligands and their linker on the photoinduced electron transfer and crosslinking processes of the two strands.,
, Eur. J. Inorg. Chem., Number 4, p.524–532, (2009)
Oxidizing Ru(II) Complexes as Irreversible and Specific Photocrosslinking Agents of Oligonucleotide Duplexes.,
, Inorg. Chem., Volume 48, Number 23, p.10988–10994, (2009)
A photoreactive ruthenium(II) complex tethered to a guanine-containing oligonucleotide: A biomolecular tool that behaves as a "Seppuku Molecule".,
, Angew. Chemie, Int. Ed., Volume 48, Number 6, p.1122–1125, (2009)
A novel conformationally constrained parallel G quadruplex.,
, ChemBioChem, Volume 9, Number 16, p.2588–2591, (2008)
RAFT Nano-constructs: surfing to biological applications.,
, J. Pept. Sci., Volume 14, Number 2, p.224–240, (2008)
Surface patterning of (bio)molecules onto the inner wall of fused-silica capillary tubes.,
, Lab Chip, Volume 8, Number 12, p.2161–2163, (2008)
Aldehydic Oligonucleotide: A Key Intermediate for the Preparation of Oligonucleotide Conjugates Through Oxime Bond Formation.,
, Nucleosides. Nucleotides Nucleic Acids, Volume 26, Number 8-9, p.883–887, (2007)
Efficient Surface Patterning of Oligonucleotides Inside a Glass Capillary through Oxime Bond Formation.,
, Bioconjug. Chem., Volume 18, Number 3, p.671–676, (2007)
New Solid Support for the Synthesis of 3'-Oligonucleotide Conjugates through Glyoxylic Oxime Bond Formation.,
, Org. Lett., Volume 9, Number 2, p.219–222, (2007)
Photo-Cross-Linking between Polymers Derivatized with Photoreactive Ruthenium-1,4,5,8-Tetraazaphenanthrene Complexes and Guanine-Containing Oligonucleotides.,
, Biomacromolecules, Volume 8, Number 11, p.3503–3510, (2007)