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Publications

91 resultats trouvés
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2020
Access to a stabilized i-motif DNA structure through four successive ligation reactions on a cyclopeptide scaffold, Devaux, Alexandre, Bonnat Laureen, Lavergne Thomas, and Defrancq Eric , Org. Biomol. Chem., 07/2020, Volume 18, p.6394-6406, (2020)
Direct Detection of Low-Molecular-Weight Compounds in 2D and 3D Aptasensors by Biolayer Interferometry, Vignon, Anthony, Flaget Arthur, Michelas Maxime, Djeghdir Mehdi, Defrancq Eric, Guerente Liliane, Spinelli Nicolas, Van der Heyden Angeline, and Dejeu Jérôme , ACS Sensors, 08/2020, Volume 5, Issue 8, p.2326 – 2330, (2020)
Flexible RuII Schiff Base Complexes: G-Quadruplex DNA Binding and Photo-Induced Cancer Cell Death, Gillard, Martin, Weynand Justin, Bonnet Hugues, Loiseau Frédérique, Decottignies Anabelle, Dejeu Jérôme, Defrancq Eric, and Elias Benjamin , Chemistry – A European Journal, Volume 26, p.13849-13860, (2020)
Post-synthetic transamination at position N4 of cytosine in oligonucleotides assembled with routinely used phosphoramidites, Lartia, Remy, Vallée Coelio, and Defrancq Eric , Org. Biomol. Chem., Volume 18, p.9632-9638, (2020)
Post-synthetic transamination at position N4 of cytosine in oligonucleotides assembled with routinely used phosphoramidites, Lartia, Remy, Vallée Coelio, and Defrancq Eric , Org. Biomol. Chem., 11/2020, p.-, (2020)
Redox-Active Bis-Cyclometalated Iridium(III) Complex as a DNA Photo-Cleaving Agent, Weynand, Justin, Moreno-Betancourt Angélica, Loiseau Frédérique, Berthet Nathalie, Defrancq Eric, and Elias Benjamin , Inorganic Chemistry, 01/2020, Volume 59, p.2426-2433, (2020)
Surface plasmon resonance study of the interaction of N-methyl mesoporphyrin IX with G-quadruplex DNA, Perenon, M, Bonnet Hugues, Lavergne Thomas, Dejeu Jérôme, and Defrancq Eric , Phys. Chem. Chem. Phys., 02/2020, Volume 22, p.4158-4164, (2020)
2018
Efficient Buchwald-Hartwig-Migita Cross-Coupling for DNA Thio-glycoconjugation., Probst, Nicolas, Lartia Remy, Thery Oceane, Alami Mouad, Defrancq Eric, and Messaoudi Samir. , Chem. - A Eur. J., Volume 24, Number 8, p.1795–1800, (2018)
Impact of Conformational Transitions on SPR Signals-Theoretical Treatment and Application in Small Analytes/Aptamer Recognition., Dejeu, Jérôme, Bonnet Hugues, Spinelli Nicolas, Defrancq Eric, Guerente Liliane, Van der Heyden Angeline, and Labbe Pierre. , J. Phys. Chem. C, Volume 122, Number 37, p.21521–21530, (2018)
Influence of the SPR Experimental Conditions on the G-Quadruplex DNA Recognition by Porphyrin Derivatives., Prado, E, Bonnat L, Bonnet Hugues, Lavergne Thomas, Van der Heyden Angeline, Pratviel G, Dejeu Jérôme, and Defrancq Eric , Langmuir, Volume 34, Number 43, p.13057–13064, (2018)
Synthesis and photophysical studies of a multivalent photoreactive RuII-calix[4]arene complex bearing RGD-containing cyclopentapeptides., Kajouj, Sofia, Marcelis Lionel, Mattiuzzi Alice, Grassin Adrien, Dufour Damien, Van Antwerpen Pierre, Boturyn Didier, Defrancq Eric, Surin Mathieu, De Winter Julien, et al. , Beilstein J. Org. Chem., Volume 14, p.1758–1768, (2018)
Towards the Development of Photo-Reactive Ruthenium(II) Complexes Targeting Telomeric G-Quadruplex DNA., Weynand, Justin, Diman Aurelie, Abraham Michael, Marcelis Lionel, Jamet Hélène, Decottignies Anabelle, Dejeu Jérôme, Defrancq Eric, and Elias Benjamin. , Chem. - A Eur. J., Volume 24, Number 72, p.19216–19227, (2018)
2016
Binding of metalloporphyrins to G-quadruplex DNA: The role of the central metal., Dejeu, Jérôme, Lavergne Thomas, Nora Jeremie Della, Defrancq Eric, and Pratviel Genevieve. , Inorganica Chim. Acta, Volume 452, p.98–103, (2016)
Efficient Inhibition of Telomerase by Nickel-Salophen Complexes., Lecarme, Laureline, Prado Enora, De Rache Aurore, Nicolau-Travers Marie-Laure, Gellon Gisèle, Dejeu Jérôme, Lavergne Thomas, Jamet Hélène, Gomez Dennis, Mergny Jean-Louis, et al. , ChemMedChem, Volume 11, Number 11, p.1133–1136, (2016)
Highly DNA-Photoreactive Ruthenium 1,4,5,8-Tetraazaphenanthrene Complex Conjugated to the TAT Peptide: Efficient Vectorization inside HeLa Cells without Phototoxicity - The Importance of Cellular Distribution., Marcelis, Lionel, Kajouj Sofia, Ghesquiere Jonathan, Fettweis Gregory, Coupienne Isabelle, Lartia Remy, Surin Mathieu, Defrancq Eric, Piette Jacques, Moucheron Cecile, et al. , Eur. J. Inorg. Chem., Volume 2016, Number 18, p.2902–2911, (2016)
Highly Sensitive Bisphenol-A Electrochemical Aptasensor Based on Poly(Pyrrole-Nitrilotriacetic Acid)-Aptamer Film., Kazane, Imen, Gorgy Karine, Gondran Chantal, Spinelli Nicolas, Zazoua Ali, Defrancq Eric, and Cosnier Serge , Anal. Chem. (Washington, DC, United States), Volume 88, Number 14, p.7268–7273, (2016)
A label-free photoelectrochemical cocaine aptasensor based on an electropolymerized ruthenium-intercalator complex., Haddache, Fatima, Le Goff Alan, Spinelli Nicolas, Gairola Priyanka, Gorgy Karine, Gondran Chantal, Defrancq Eric, and Cosnier Serge , Electrochim. Acta, Volume 219, p.82–87, (2016)
Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties., Flack, Theodore, Constantin Thibaut, Penasse Sylvain, Dejeu Jérôme, Gennaro Béatrice, Jourdan Muriel, Laguerre Aurelien, Pirrotta Marc, Monchaud David, Spinelli Nicolas, et al. , Chem. - A Eur. J., Volume 22, Number 5, p.1760–1767, (2016)
Templated Formation of Discrete RNA and DNA:RNA Hybrid G-Quadruplexes and Their Interactions with Targeting Ligands., Bonnat, Laureen, Dejeu Jérôme, Bonnet Hugues, Gennaro Béatrice, Jarjayes Olivier, Thomas Fabrice, Lavergne Thomas, and Defrancq Eric , Chem. - A Eur. J., Volume 22, Number 9, p.3139–3147, (2016)
2015
Assessment of the Full Compatibility of Copper(I)-Catalyzed Alkyne-Azide Cycloaddition and Oxime Click Reactions for bis-Labelling of Oligonucleotides., Estalayo-Adrian, Sandra, Lartia Remy, Meyer Albert, Vasseur Jean-Jacques, Morvan Francois, and Defrancq Eric , ChemistryOpen, Volume 4, Number 2, p.169–173, (2015)
Cobalt(III)porphyrin to target G-quadruplex DNA., Sabater, Laurent, Fang Pei-Ju, Chang Chi-Fon, De Rache Aurore, Prado Enora, Dejeu Jérôme, Garofalo Antonio, Lin Jung-Hsin, Mergny Jean-Louis, Defrancq Eric, et al. , Dalt. Trans., Volume 44, Number 8, p.3701–3707, (2015)
Construction of anti-parallel G-quadruplexes through sequential templated click., Bonnet, Romaric, Lavergne Thomas, Gennaro Béatrice, Spinelli Nicolas, and Defrancq Eric , Chem. Commun. (Cambridge, United Kingdom), Volume 51, Number 23, p.4850–4853, (2015)
Macrocyclic Host-Dye Reporter for Sensitive Sandwich-Type Fluorescent Aptamer Sensor., Yang, Cheng, Spinelli Nicolas, Perrier Sandrine, Defrancq Eric, and Peyrin Eric. , Anal. Chem. (Washington, DC, United States), Volume 87, Number 6, p.3139–3143, (2015)
The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells., Sabater, Laurent, Nicolau-Travers Marie-Laure, De Rache Aurore, Prado Enora, Dejeu Jérôme, Bombarde Oriane, Lacroix Joris, Calsou Patrick, Defrancq Eric, Mergny Jean-Louis, et al. , JBIC, J. Biol. Inorg. Chem., Volume 20, Number 4, p.729–738, (2015)
Parameters influencing the photo-induced electron transfer from tryptophan-containing peptides to a RuII complex: a systematic study., Garnir, Kevin, Estalayo-Adrian Sandra, Lartia Remy, De Winter Julien, Defrancq Eric, Surin Mathieu, Lemaur Vincent, Gerbaux Pascal, and Moucheron Cecile. , Faraday Discuss., Volume 185, p.267–284, (2015)
Sensor Based on Aptamer Folding to Detect Low-Molecular Weight Analytes., Osypova, Alina, Thakar Dhruv, Dejeu Jérôme, Bonnet Hugues, Van der Heyden Angeline, Dubacheva Galina V., Richter Ralf P., Defrancq Eric, Spinelli Nicolas, Guerente Liliane, et al. , Anal. Chem. (Washington, DC, United States), Volume 87, Number 15, p.7566–7574, (2015)
2013
Characterization of a modified gold platform for the development of a label-free anti-thrombin aptasensor., Jalit, Yamile, Gutierrez Fabiana A., Dubacheva Galina V., Goyer Cedric, Guerente Liliane, Defrancq Eric, Labbe Pierre, Rivas Gustavo A., and Rodriguez Marcela C. , Biosens. Bioelectron., Volume 41, p.424–429, (2013)
Closer to nature: an ATP-driven bioinspired catalytic oxidation process., Stefan, Loic, Duret Damien, Spinelli Nicolas, Defrancq Eric, and Monchaud David. , Chem. Commun. (Cambridge, United Kingdom), Volume 49, Number 15, p.1500–1502, (2013)
Electrogenerated trisbipyridyl Ru(II)-/nitrilotriacetic-polypyrene copolymer for the easy fabrication of label-free photoelectrochemical immunosensor and aptasensor: Application to the determination of thrombin and anti-cholera toxin antibody., Yao, Wenjuan, Le Goff Alan, Spinelli Nicolas, Holzinger Michael, Diao Guo-Wang, Shan Dan, Defrancq Eric, and Cosnier Serge , Biosens. Bioelectron., Volume 42, p.556–562, (2013)
Evaluation of a new biocompatible poly(N-(morpholino ethyl methacrylate))-based copolymer for the delivery of ruthenium oligonucleotides, targeting HPV16 E6 oncogene., Reschner, Anca, Shim Yong Ho, Dubois Philippe, Delvenne Philippe, Evrard Brigitte, Marcelis Lionel, Moucheron Cecile, De Mesmaeker Andree Kirsch-, Defrancq Eric, Raes Martine, et al. , J. Biomed. Nanotechnol., Volume 9, Number 8, p.1432–1440, (2013)
Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications., Spinelli, Nicolas, Defrancq Eric, and Morvan Francois. , Chem. Soc. Rev., Volume 42, Number 11, p.4557–4573, (2013)
Label-free impedimetric thrombin sensor based on poly(pyrrole-nitrilotriacetic acid)-aptamer film, Xu, Hui, Gorgy Karine, Gondran Chantal, Le Goff Alan, Spinelli Nicolas, Lopez Christian, Defrancq Eric, and Cosnier Serge , Biosensors and Bioelectronics, Volume 41, p.90 - 95, (2013)
Oligonucleotide Functionalization of Hollow Triangular Gold Silver Alloy Nanoboxes., Keegan, Gemma L., Aherne Damian, Defrancq Eric, Gun'ko Yurii K., and Kelly John M. , J. Phys. Chem. C, Volume 117, Number 1, p.669–676, (2013)
Optical properties and in vitro biological studies of oligonucleotide-modified quantum dots., Gerard, Valerie A., Freeley Mark, Defrancq Eric, Fedorov Anatoly V., and Gun'ko Yurii K. , J. Nanomater., p.463951, 11 pp., (2013)
Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53., Reschner, A, Bontems S, Le Gac Stephane, Lambermont J, Marcelis L, Defrancq Eric, Hubert P, Moucheron C, A De Mesmaeker Kirsch-, Raes M, et al. , Gene Ther., Volume 20, Number 4, p.435–443, (2013)
Synthesis and characterization of oligonucleotide conjugates bearing electroactive labels., Moreau, Julie, Dendane Nabil, Schollhorn Bernd, Spinelli Nicolas, Fave Claire, and Defrancq Eric , Bioorg. Med. Chem. Lett., Volume 23, Number 4, p.955–958, (2013)
Use of T-2 toxin-immobilized amine-activated beads as an efficient affinity purification matrix for the isolation of specific IgY., Edupuganti, Soujanya Ratna, Edupuganti Om Prakash, O'Kennedy Richard, Defrancq Eric, and Boullanger Stephanie. , J. Chromatogr. B Anal. Technol. Biomed. Life Sci., Volume 923-924, p.98–101, (2013)
What Are the Parameters Controlling Inter- vs. Intra-Strand DNA Photodamage with Ru-TAP Oligonucleotides?., Le Gac, Stephane, Surin Mathieu, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Volume 2013, Number 2, p.208–216, (2013)
2011
Controlled Density Patterning of Tolylterpyridine-Tagged Oligonucleotides., Tuccitto, Nunzio, Giamblanco Nicoletta, Ghosh Sumana, Spampinato Valentina, Labbe Pierre, Dumy Pascal, Quici Silvio, Marletta Giovanni, Defrancq Eric, and Licciardello Antonino. , Langmuir, Volume 27, Number 14, p.8595–8599, (2011)
Improvement of porphyrins for G-quadruplex DNA targeting., Romera, Carmen, Bombarde Oriane, Bonnet Romaric, Gomez Dennis, Dumy Pascal, Calsou Patrick, Gwan Jean-Fang, Lin Jung-Hsin, Defrancq Eric, and Pratviel Genevieve. , Biochimie, Volume 93, Number 8, p.1310–1317, (2011)
Methods for investigating G-quadruplex DNA/ligand interactions., Murat, Pierre, Singh Yashveer, and Defrancq Eric , Chem. Soc. Rev., Volume 40, Number 11, p.5293–5307, (2011)
Plasmon-induced CD response of oligonucleotide-conjugated metal nanoparticles., Gerard, Valerie A., Gun'ko Yurii K., Defrancq Eric, and Govorov Alexander O. , Chem. Commun. (Cambridge, United Kingdom), Volume 47, Number 26, p.7383–7385, (2011)
The Use of a Peptidic Scaffold for the Formation of Stable Guanine Tetrads: Control of a H-bonded Pattern in Water., Murat, Pierre, Gennaro Béatrice, Garcia Julian, Spinelli Nicolas, Dumy Pascal, and Defrancq Eric , Chem. - A Eur. J., Volume 17, Number 21, p.5791–5795, S5791/1–S5791/21, (2011)
Versatile Introduction of Azido Moiety into Oligonucleotides through Diazo Transfer Reaction., Lartia, Remy, Murat Pierre, Dumy Pascal, and Defrancq Eric , Org. Lett., Volume 13, Number 20, p.5672–5675, (2011)
2010
Label-free femtomolar detection of target DNA by impedimetric DNA sensor based on poly(pyrrole-nitrilotriacetic acid) film., Baur, Jessica, Gondran Chantal, Holzinger Michael, Defrancq Eric, Perrot Hubert, and Cosnier Serge , Anal. Chem. (Washington, DC, United States), Volume 82, Number 3, p.1066–1072, (2010)
Metal-Complex/DNA Conjugates: A Versatile Building Block for DNA Nanoarrays., Ghosh, Sumana, and Defrancq Eric , Chem. - A Eur. J., Volume 16, Number 43, p.12780–12787, (2010)
Molecular engineering of biomolecules for nanobio-sciences., Renaudet, Olivier, Garcia Julian, Boturyn Didier, Spinelli Nicolas, Defrancq Eric, Labbe Pierre, and Dumy Pascal , Int. J. Nanotechnol., Volume 7, Number 4/5/6/7/8, p.738–752, (2010)
Oligonucleotide Sequential Bis-Conjugation via Click-Oxime and Click-Huisgen Procedures., Meyer, Albert, Spinelli Nicolas, Dumy Pascal, Vasseur Jean-Jacques, Morvan Francois, and Defrancq Eric , J. Org. Chem., Volume 75, Number 11, p.3927–3930, (2010)
Photoinduced Electron Transfer from Tryptophan to RuIITAP Complexes: The Primary Process for Photo-Cross-Linking with Oligopeptides., Rebarz, Mateusz, Ghesquiere Jonathan, Boisdenghien Arnaud, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Inorg. Chem., Volume 49, Number 23, p.10867–10874, (2010)
Photo-reactive RuII-oligonucleotide conjugates: influence of an intercalating ligand on the inter- and intra-strand photo-ligation processes., Le Gac, Stephane, Foucart Martin, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Dalt. Trans., Volume 39, Number 40, p.9672–9683, (2010)
Recent developments in oligonucleotide conjugation., Singh, Yashveer, Murat Pierre, and Defrancq Eric , Chem. Soc. Rev., Volume 39, Number 6, p.2054–2070, (2010)
A Rigid Dinuclear Ruthenium(II) Complex as an Efficient Photoactive Agent for Bridging Two Guanine Bases of a Duplex or Quadruplex Oligonucleotide., Rickling, Stephane, Ghisdavu Liana, Pierard Frederic, Gerbaux Pascal, Surin Mathieu, Murat Pierre, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Chem. - A Eur. J., Volume 16, Number 13, p.3951–3961, S3951/1–S3951/9, (2010)
Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies., Murat, Pierre, Bonnet Romaric, Van der Heyden Angeline, Spinelli Nicolas, Labbe Pierre, Monchaud David, Teulade-Fichou Marie-Paule, Dumy Pascal, and Defrancq Eric , Chem. - A Eur. J., Volume 16, Number 20, p.6106–6114, S6106/1–S6106/16, (2010)
2009
Design and synthesis of novel hybrid metal complex-DNA conjugates: Key building blocks for multimetallic linear DNA nanoarrays., Ghosh, Sumana, Pignot-Paintrand Isabelle, Dumy Pascal, and Defrancq Eric , Org. Biomol. Chem., Volume 7, Number 13, p.2729–2737, (2009)
Efficient conjugation of oligonucleotides through aromatic oxime formation., Murat, Pierre, Spinelli Nicolas, Dumy Pascal, and Defrancq Eric , Bioorg. Med. Chem. Lett., Volume 19, Number 23, p.6534–6537, (2009)
Oligonucleotide duplexes with tethered photoreactive ruthenium(II) complexes: influence of the ligands and their linker on the photoinduced electron transfer and crosslinking processes of the two strands., Deroo, Stephanie, Le Gac Stephane, Ghosh Sumana, Villien Mathilde, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, Dumy Pascal, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Number 4, p.524–532, (2009)
Oxidizing Ru(II) Complexes as Irreversible and Specific Photocrosslinking Agents of Oligonucleotide Duplexes., Ghizdavu, Liana, Pierard Frederic, Rickling Stephane, Aury Sabrina, Surin Mathieu, Beljonne David, Lazzaroni Roberto, Murat Pierre, Defrancq Eric, Moucheron Cecile, et al. , Inorg. Chem., Volume 48, Number 23, p.10988–10994, (2009)
A photoreactive ruthenium(II) complex tethered to a guanine-containing oligonucleotide: A biomolecular tool that behaves as a "Seppuku Molecule"., Le Gac, Stephane, Rickling Stephane, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Angew. Chemie, Int. Ed., Volume 48, Number 6, p.1122–1125, (2009)