Département de chimie moléculaire

Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer, Achilli, Silvia, Berthet Nathalie, and Renaudet Olivier , RSC Chem. Biol., 03/2021, Volume 2, p.713-724 , (2021)

Chemical synthesis and immunological evaluation of new generation multivalent anticancer vaccines based on a Tn antigen analogue, Pifferi, Carlo, Ruiz-de-Angulo Ane, Goyard David, Tiertant Claire, Sacristán Nagore, Barriales Diego, Berthet Nathalie, Anguita Juan, Renaudet Olivier, and Fernández-Tejada Alberto , Chem. Sci., 04/2020, Volume 11, p.4488 - 4498 , (2020)

Chemical synthesis, DNA incorporation and biological study of a new photo-cleavable 2'-deoxyadenosine mimic., Berthet, Nathalie, Crey-Desbiolles Caroline, Kotera Mitsuharu, and Dumy Pascal , Nucleic Acids Res., Volume 37, Number 16, p.5237–5245, (2009)

Copper(II) complexes of N3O tripodal ligands appended with pyrene and polyamine groups: Anti-proliferative and nuclease activities., Serre, Doti, Erbek Sule, Berthet Nathalie, Ronot Xavier, Martel-Frachet Veronique, and Thomas Fabrice , J. Inorg. Biochem., Volume 179, p.121–134, (2018)

Cyclopeptide scaffolds in carbohydrate-based synthetic vaccines., Pifferi, Carlo, Berthet Nathalie, and Renaudet Olivier , Biomater. Sci., Volume 5, Number 5, p.953–965, (2017)

Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters., Bossu, Isabelle, Sulc Miroslav, Krenek Karel, Dufour Emilie, Garcia Julian, Berthet Nathalie, Dumy Pascal, Kren Vladimir, and Renaudet Olivier , Org. Biomol. Chem., Volume 9, Number 6, p.1948–1959, (2011)

Divergent and convergent synthesis of GalNAc-conjugated dendrimers using dual orthogonal ligations., Thomas, Baptiste, Pifferi Carlo, Daskhan Gour Chand, Fiore Michele, Berthet Nathalie, and Renaudet Olivier , Org. Biomol. Chem., Volume 13, Number 47, p.11529–11538, (2015)

Expanding the scope of oxime ligation: facile synthesis of large cyclopeptide-based glycodendrimers., Thomas, Baptiste, Berthet Nathalie, Garcia Julian, Dumy Pascal, and Renaudet Olivier , Chem. Commun. (Cambridge, United Kingdom), Volume 49, Number 92, p.10796–10798, (2013)

Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol-ene coupling. The observation of a striking glycoside cluster effect., Conte, Mauro Lo, Staderini Samuele, Chambery Angela, Berthet Nathalie, Dumy Pascal, Renaudet Olivier, Marra Alberto, and Dondoni Alessandro. , Org. Biomol. Chem., Volume 10, Number 16, p.3269–3277, (2012)

Heterovalent Glycodendrimers as Epitope Carriers for Antitumor Synthetic Vaccines., Pifferi, Carlo, Thomas Baptiste, Goyard David, Berthet Nathalie, and Renaudet Olivier , Chem. - A Eur. J., Volume 23, Number 64, p.16283–16296, (2017)

High Affinity Glycodendrimers for the Lectin LecB from Pseudomonas aeruginosa., Berthet, Nathalie, Thomas Baptiste, Bossu Isabelle, Dufour Emilie, Gillon Emilie, Garcia Julian, Spinelli Nicolas, Imberty Anne, Dumy Pascal, and Renaudet Olivier , Bioconjug. Chem., Volume 24, Number 9, p.1598–1611, (2013)

A high-throughput screen for detection of compound-dependent phosphodiester bond cleavage at abasic sites, Rideout, Marc C., Liet Benjamin, Gasparutto Didier, and Berthet Nathalie , Analytical Biochemistry, Volume 513, p.93-97, (2016)

Metabolic labelling of cancer cells with glycodendrimers stimulate immune-mediated cytotoxicity, Goyard, David, Diriwari Peremobowei Iyanu, and Berthet Nathalie , RSC Med. Chem., Volume 13, p.72-78, (2022)

Multifunctional Glycoconjugates for Recruiting Natural Antibodies against Cancer Cells, Liet, Benjamin, Laigre Eugenie, Goyard David, Todaro Biagio, Tiertant Claire, Boturyn Didier, Berthet Nathalie, and Renaudet Olivier , Chemistry – A European Journal, Volume 25, p.15508-15515, (2019)

Multifunctional Glycoconjugates for Recruiting Natural Antibodies against Cancer Cells., Liet, Benjamin, Laigre Eugenie, Goyard David, Todaro Biagio, Tiertant Claire, Boturyn Didier, Berthet Nathalie, and Renaudet Olivier , Chem. - Eur. J., Volume 25, p.15508–15515, (2019)

Multivalent glycocyclopeptides: toward nano-sized glycostructures., Daskhan, Gour Chand, Berthet Nathalie, Thomas Baptiste, Fiore Michele, and Renaudet Olivier , Carbohydr. Res., Volume 405, p.13–22, (2015)

New glycopolymers as multivalent systems for lectin recognition., Fiore, Michele, Berthet Nathalie, Renaudet Olivier, and Barbier Valessa. , Medchemcomm, Volume 5, Number 8, p.1202–1207, (2014)

Nuclease and anti-proliferative activities of copper(II) complexes of N3O tripodal ligands involving a sterically hindered phenolate., Berthet, Nathalie, Martel-Frachet Veronique, Michel Fabien, Philouze Christian, Hamman Sylvain, Ronot Xavier, and Thomas Fabrice , Dalt. Trans., Volume 42, Number 23, p.8468–8483, (2013)

Redox-Active Bis-Cyclometalated Iridium(III) Complex as a DNA Photo-Cleaving Agent, Weynand, Justin, Moreno-Betancourt Angélica, Loiseau Frédérique, Berthet Nathalie, Defrancq Eric, and Elias Benjamin , Inorganic Chemistry, 01/2020, Volume 59, p.2426-2433, (2020)

Structural influence of antibody recruiting glycodendrimers (ARGs) on antitumoral cytotoxicity, Todaro, Biagio, Achilli Silvia, Liet Benjamin, Laigre Eugenie, Tiertant Claire, Goyard David, Berthet Nathalie, and Renaudet Olivier , Biomater. Sci., 04/2021, Volume 9, p.4076-4085 , (2021)

Synthesis of Glycocyclopeptides by Click Chemistry and Inhibition Assays with Lectins., Bossu, Isabelle, Berthet Nathalie, Dumy Pascal, and Renaudet Olivier , J. Carbohydr. Chem., Volume 30, Number 7-9, p.458–468, (2011)

Tetravalent glycocyclopeptide with nanomolar affinity to wheat germ agglutinin., Fiore, Michele, Berthet Nathalie, Marra Alberto, Gillon Emilie, Dumy Pascal, Dondoni Alessandro, Imberty Anne, and Renaudet Olivier , Org. Biomol. Chem., Volume 11, Number 41, p.7113–7122, (2013)

Thiol-ene and thiol-yne-based synthesis of glycodendrimers as nanomolar inhibitors of wheat germ agglutinin., Ghirardello, Mattia, Oeberg Kim, Staderini Samuele, Renaudet Olivier, Berthet Nathalie, Dumy Pascal, Hed Yvonne, Marra Alberto, Malkoch Michael, and Dondoni Alessandro. , J. Polym. Sci. Part A Polym. Chem., Volume 52, Number 17, p.2422–2433, (2014)

Thiyl Glycosylation of Propargylated Octasilsesquioxane: Synthesis and Lectin-Binding Properties of Densely Glycosylated Clusters on a Cubic Platform., Marra, Alberto, Staderini Samuele, Berthet Nathalie, Dumy Pascal, Renaudet Olivier, and Dondoni Alessandro. , European J. Org. Chem., Volume 2013, Number 6, p.1144–1149, (2013)

Towards the preparation of synthetic outer membrane vesicle models with micromolar affinity to wheat germ agglutinin using a dialkyl thioglycoside, Fayolle, Dimitri, Berthet Nathalie, Doumeche Bastien, Renaudet Olivier, Strazewski Peter, and Fiore Michele , Beilstein Journal of Organic Chemistry, Volume 15, p.937-946, (2019)

Towards the preparation of synthetic outer membrane vesicle models with micromolar affinity to wheat germ agglutinin using a dialkyl thioglycoside., Fayolle, Dimitri, Berthet Nathalie, Doumeche Bastien, Renaudet Olivier, Strazewski Peter, and Fiore Michele. , Beilstein J. Org. Chem., Volume 15, p.937–946, (2019)