Département de chimie moléculaire

In vivo noninvasive optical imaging of receptor-mediated RGD internalization using self-quenched Cy5-labeled RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Razkin Jesus, Josserand Veronique, Boturyn Didier, Grichine Alexei, Texier Isabelle, Favrot Marie-Christine, Dumy Pascal, and Coll Jean-Luc. , Mol. Imaging, Volume 6, Number 1, p.43–55, (2007)

Synthesis and biological characterization of targeted pro-apoptotic peptide., Foillard, Stephanie, Jin Zhao-hui, Garanger Elisabeth, Boturyn Didier, Favrot Marie-Christine, Coll Jean-Luc, and Dumy Pascal , ChemBioChem, Volume 9, Number 14, p.2326–2332, (2008)

RGD-cyclam conjugate: Synthesis and potential application for positron emission tomography., Galibert, Mathieu, Jin Zhao-hui, Furukawa Takako, Fukumura Toshimitsu, Saga Tsuneo, Fujibayashi Yasuhisa, Dumy Pascal, and Boturyn Didier , Bioorg. Med. Chem. Lett., Volume 20, Number 18, p.5422–5425, (2010)

Noninvasive visualization and quantification of tumor $\alpha$V$\beta$3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Galibert Mathieu, Boturyn Didier, Coll Jean-Luc, Fukumura Toshimitsu, Saga Tsuneo, Dumy Pascal, and Fujibayashi Yasuhisa. , Nucl. Med. Biol., Volume 38, Number 4, p.529–540, (2011)

Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Claron Michael, Boturyn Didier, Coll Jean-Luc, Fukumura Toshimitsu, Fujibayashi Yasuhisa, Dumy Pascal, and Saga Tsuneo. , Angiogenesis, Volume 15, Number 4, p.569–580, (2012)

Micro-positron emission tomography/contrast-enhanced computed tomography imaging of orthotopic pancreatic tumor-bearing mice using the $\alpha$v$\beta$3 integrin tracer 64Cu-labeled cyclam-RAFT-c(-RGDfK-)4., Aung, Winn, Jin Zhao-hui, Furukawa Takako, Claron Michael, Boturyn Didier, Sogawa Chizuru, Tsuji Atsushi B., Wakizaka Hidekatsu, Fukumura Toshimitsu, Fujibayashi Yasuhisa, et al. , Mol. Imaging, Volume 12, Number 6, p.376–387, (2013)

PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of 64Cu-cyclam-RAFT-c(-RGDfK-)4in vivo., Jin, Zhao-hui, Furukawa Takako, Sogawa Chizuru, Claron Michael, Aung Winn, Tsuji Atsushi B., Wakizaka Hidekatsu, Zhang Ming-Rong, Boturyn Didier, Dumy Pascal, et al. , Eur. J. Pharm. Biopharm., Volume 86, Number 3, p.478–486, (2014)

$\alpha$V$\beta$3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Degardin Melissa, Sugyo Aya, Tsuji Atsushi B., Yamasaki Tomoteru, Kawamura Kazunori, Fujibayashi Yasuhisa, Zhang Ming-Rong, Boturyn Didier, et al. , Mol. Cancer Ther., Volume 15, Number 9, p.2076–2085, (2016)

67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice., Jin, Zhao-hui, Furukawa Takako, Ohya Tomoyuki, Degardin Melissa, Sugyo Aya, Tsuji Atsushi B., Fujibayashi Yasuhisa, Zhang Ming-Rong, Higashi Tatsuya, Boturyn Didier, et al. , Nucl. Med. Commun., Volume 38, Number 4, p.347–355, (2017)

Positron emission tomography of cerebral angiogenesis and TSPO expression in a mouse model of chronic hypoxia., Kanno, Iwao, Seki Chie, Takuwa Hiroyuki, Jin Zhao-hui, Boturyn Didier, Dumy Pascal, Furukawa Takako, Saga Tsuneo, Ito Hiroshi, and Masamoto Kazuto. , J. Cereb. Blood Flow Metab., Volume 38, Number 4, p.687–696, (2018)

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model., Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Sugyo Aya, Yoshii Yukie, Nagatsu Kotaro, Zhang Ming-Rong, Fujibayashi Yasuhisa, Dumy Pascal, Boturyn Didier, et al. , EJNMMI Res., Volume 8, Number 1, p.1–10, (2018)

Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer, Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Sugyo Aya, Obara Satoshi, Wakizaka Hidekatsu, Nagatsu Kotaro, Hu Kuan, Zhang Ming-Rong, Dumy Pascal, et al. , Clinical Cancer Research, 09/2020, Volume 26, Issue 23, p.6230-6241, (2020)

Multiplexed Imaging Reveals the Spatial Relationship of the Extracellular Acidity-Targeting pHLIP with Necrosis, Hypoxia, and the Integrin-Targeting cRGD Peptide, Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Dumy Pascal, Boturyn Didier, and Higashi Tatsuya , Cells, 11/2022, Volume 11, (2022)