Département de chimie moléculaire

Concise Synthesis of 2-Amino-4(3H)-quinazolinones from Simple (Hetero)aromatic Amines., Zeghida, Walid, Debray Julien, Chierici Sabine, Dumy Pascal, and Demeunynck Martine , J. Org. Chem., Volume 73, Number 6, p.2473–2475, (2008)

Functionalization of the A ring of pyridoacridine as a route toward greater structural diversity. Synthesis of an octacyclic analogue of eilatin., Bouffier, Laurent, Dinica Rodica, Debray Julien, Dumy Pascal, and Demeunynck Martine , Bioorg. Med. Chem. Lett., Volume 19, Number 16, p.4836–4838, (2009)

Montmorillonite K-10 catalyzed cyclization of N-ethoxycarbonyl-N'-arylguanidines: Access to pyrimido[4,5-c]carbazole and pyrimido[5,4-b]indole derivatives., Debray, Julien, Zeghida Walid, Baldeyrou Brigitte, Mahieu Christine, Lansiaux Amelie, and Demeunynck Martine , Bioorg. Med. Chem. Lett., Volume 20, Number 14, p.4244–4247, (2010)

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras, Desroches-Castan, Agnes, Quelard Delphine, Demeunynck Martine, Constant Jean-François, Dong Chongling, Keramidas Michelle, Coll Jean-Luc, Barette Caroline, Lafanechere Laurence, and Feige Jean-Jacques , Oncotarget, Volume 6, p.5382–5411, (2015)

Proflavine derivatives as fluorescent imaging agents of amyloid deposits., Garin, Dominique, Oukhatar Fatima, Mahon Andrew B., Try Andrew C., Dubois-Dauphin Michel, Laferla Frank M., Demeunynck Martine, Sallanon Marcelle Moulin, and Chierici Sabine , Bioorg. Med. Chem. Lett., Volume 21, Number 8, p.2203–2206, (2011)

Reactivity of Pyrido[4,3,2-kl]acridines: Regioselective Formation of 6-Substituted Derivatives., Bouffier, Laurent, Demeunynck Martine, Milet Anne, and Dumy Pascal , J. Org. Chem., Volume 69, Number 23, p.8144–8147, (2004)

Swift and Efficient Synthesis of 4-Phenylquinazolines: Involvement of N-Heterocyclic Carbene in the Key Cyclization Step., Debray, Julien, Leveque Jean-Marc, Philouze Christian, Draye Micheline, and Demeunynck Martine , J. Org. Chem., Volume 75, Number 6, p.2092–2095, (2010)

Synthesis and evaluation of fused bispyrimidinoacridines as novel pentacyclic analogues of quadruplex-binder BRACO-19., Debray, Julien, Zeghida Walid, Jourdan Muriel, Monchaud David, Dheu-Andries Marie-Louise, Dumy Pascal, Teulade-Fichou Marie-Paule, and Demeunynck Martine , Org. Biomol. Chem., Volume 7, Number 24, p.5219–5228, (2009)

Synthesis of N-acridinyl-N'-alkylguanidines: Dramatic influence of amine to guanidine replacement on the physicochemical properties., Zeghida, Walid, Debray Julien, Michel Carine, Milet Anne, Dumy Pascal, and Demeunynck Martine , Bioorg. Med. Chem. Lett., Volume 18, Number 17, p.4779–4782, (2008)

Unusual cellular uptake of cytotoxic 4-hydroxymethyl-3-aminoacridine., Peixoto, Paul, Zeghida Walid, Carrez Daniele, Di Wu Ting-, Wattez Nicole, Croisy Alain, Demeunynck Martine, Guerquin-Kern Jean-Luc, and Lansiaux Amelie. , Eur. J. Med. Chem., Volume 44, Number 11, p.4758–4763, (2009)

Preparation of 1,4-disubstituted piperazines, 1-naphthylsulfonamide and 1,8-naphthalimide derivatives as antiangiogenic agents, their pharmaceutical compositions containing them, and their use for treating particularly cancers., Feige, Jean-Jacques, Castan Agnes, Quelard Delphine, Demeunynck Martine, Constant Jean-François, and Barette Caroline. , (2012)