106 resultats trouvés
Auteur Titre Type [ Année
] Filtres: Auteur est Pascal Dumy [Clear All Filters]
Positron emission tomography of cerebral angiogenesis and TSPO expression in a mouse model of chronic hypoxia.,
, J. Cereb. Blood Flow Metab., Volume 38, Number 4, p.687–696, (2018)
67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice.,
, Nucl. Med. Commun., Volume 38, Number 4, p.347–355, (2017)
An oxime-based glycocluster microarray.,
, Org. Biomol. Chem., Volume 15, Number 24, p.5135–5139, (2017)
Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model.,
, Mol. Ther., Volume 25, Number 2, p.534–546, (2017)
$\alpha$V$\beta$3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.,
, Mol. Cancer Ther., Volume 15, Number 9, p.2076–2085, (2016)
Influence of Pre-organised Architecture on Cell Adhesion by Using Multivalent RGD Compounds.,
, ChemBioChem, Volume 17, Number 6, p.515–520, (2016)
Access to bifunctionalized biomolecular platforms using oxime ligation.,
, Carbohydr. Res., Volume 393, p.9–14, (2014)
Co-liposomes comprising a lipidated multivalent RGD-peptide and a cationic gemini cholesterol induce selective gene transfection in $\alpha$v$\beta$3 and $\alpha$v$\beta$5 integrin receptor-rich cancer cells.,
, J. Mater. Chem. B Mater. Biol. Med., Volume 2, Number 35, p.5758–5767, (2014)
Oxime Ligation: A Chemoselective Click-Type Reaction for Accessing Multifunctional Biomolecular Constructs.,
, Chem. - A Eur. J., Volume 20, Number 1, p.34–41, (2014)
PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of 64Cu-cyclam-RAFT-c(-RGDfK-)4in vivo.,
, Eur. J. Pharm. Biopharm., Volume 86, Number 3, p.478–486, (2014)
Redox-driven host-guest interactions allow the controlled release of captured cells on RGD-functionalized surfaces.,
, ChemBioChem, Volume 15, Number 3, p.377–381, (2014)
Re-evaluation of binding properties of recombinant lymphocyte receptors NKR-P1A and CD69 to chemically synthesized glycans and peptides.,
, Int. J. Mol. Sci., Volume 15, Number 1, p.1271–1283, 13 pp., (2014)
Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells [Retraction of document cited in CA152:592290].,
, J. Am. Chem. Soc., Volume 136, Number 3, p.1156, (2014)
Thiol-ene and thiol-yne-based synthesis of glycodendrimers as nanomolar inhibitors of wheat germ agglutinin.,
, J. Polym. Sci. Part A Polym. Chem., Volume 52, Number 17, p.2422–2433, (2014)
Engineering of biomolecules for sensing and imaging applications.,
, J. Drug Deliv. Sci. Technol., Volume 23, Number 1, p.5–15, (2013)
Expanding the scope of oxime ligation: facile synthesis of large cyclopeptide-based glycodendrimers.,
, Chem. Commun. (Cambridge, United Kingdom), Volume 49, Number 92, p.10796–10798, (2013)
High Affinity Glycodendrimers for the Lectin LecB from Pseudomonas aeruginosa.,
, Bioconjug. Chem., Volume 24, Number 9, p.1598–1611, (2013)
In vivo molecular imaging of atherosclerotic lesions in ApoE-/- mice using VCAM-1-specific, 99Tc-labeled peptidic sequences.,
, J. Nucl. Med., Volume 54, Number 8, p.1442–1449, (2013)
Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate.,
, Org. Biomol. Chem., Volume 11, Number 3, p.448–452, (2013)
Micro-positron emission tomography/contrast-enhanced computed tomography imaging of orthotopic pancreatic tumor-bearing mice using the $\alpha$v$\beta$3 integrin tracer 64Cu-labeled cyclam-RAFT-c(-RGDfK-)4.,
, Mol. Imaging, Volume 12, Number 6, p.376–387, (2013)
Multivalent glyco(cyclo)peptides.,
, Chem. Soc. Rev., Volume 42, Number 11, p.4599–4612, (2013)
Near-infrared optical guided surgery of highly infiltrative fibrosarcomas in cats using an anti-$\alpha$vss3 integrin molecular probe.,
, Cancer Lett. (New York, NY, United States), Volume 334, Number 2, p.188–195, (2013)
Synthesis of multi-antigenic platforms as vaccine candidates against cancers.,
, New J. Chem., Volume 37, Number 2, p.286–289, (2013)
Tetravalent glycocyclopeptide with nanomolar affinity to wheat germ agglutinin.,
, Org. Biomol. Chem., Volume 11, Number 41, p.7113–7122, (2013)
Thiyl Glycosylation of Propargylated Octasilsesquioxane: Synthesis and Lectin-Binding Properties of Densely Glycosylated Clusters on a Cubic Platform.,
, European J. Org. Chem., Volume 2013, Number 6, p.1144–1149, (2013)
Amphipol mediated surface immobilization of FhuA: a platform for label-free detection of the bacteriophage protein pb5.,
, Chem. Commun. (Cambridge, United Kingdom), Volume 48, Number 48, p.6037–6039, (2012)
Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine-thymine mismatch.,
, Nucleic Acids Res., Volume 40, Number 11, p.5115–5128, (2012)
Fluorescent molecules for surgery.,
, Actual. Chim., Volume 366, p.23–28, (2012)
Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol-ene coupling. The observation of a striking glycoside cluster effect.,
, Org. Biomol. Chem., Volume 10, Number 16, p.3269–3277, (2012)
Multilayer assemblies of polyelectrolyte-gold nanoparticles for the electrocatalytic oxidation and detection of arsenic(III).,
, J. Colloid Interface Sci., Volume 383, Number 1, p.130–139, (2012)
Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe 64Cu-cyclam-RAFT-c(-RGDfK-)4.,
, Angiogenesis, Volume 15, Number 4, p.569–580, (2012)
Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin $\alpha$v$\beta$3 targeting using single photon emission computed tomography and optical imaging.,
, Cancer Sci., Volume 103, Number 6, p.1105–1110, (2012)
Synthesis of heteroglycoclusters by using orthogonal chemoselective ligations.,
, Beilstein J. Org. Chem., Volume 8, p.421–427, No. 47, (2012)
Access to Biomolecular Assemblies through One-Pot Triple Orthogonal Chemoselective Ligations.,
, Angew. Chemie, Int. Ed., Volume 50, Number 8, p.1901–1904, S1901/1–S1901/32, (2011)
Amyloidogenesis highlighted by designed peptides forming supramolecular self-assemblies.,
, Chem. Sci., Volume 2, Number 7, p.1293–1300, (2011)
Clicked tacrine conjugates as acetylcholinesterase and $\beta$-amyloid directed compounds.,
, Org. Biomol. Chem., Volume 9, Number 4, p.1140–1147, (2011)
Controlled Density Patterning of Tolylterpyridine-Tagged Oligonucleotides.,
, Langmuir, Volume 27, Number 14, p.8595–8599, (2011)
Cyclic neoglycodecapeptides: how to increase their inhibitory activity and selectivity on lectin/toxin binding to a glycoprotein and cells.,
, J. Pept. Sci., Volume 17, Number 6, p.427–437, (2011)
Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters.,
, Org. Biomol. Chem., Volume 9, Number 6, p.1948–1959, (2011)
Hepatocyte Targeting and Intracellular Copper Chelation by a Thiol-Containing Glycocyclopeptide.,
, J. Am. Chem. Soc., Volume 133, Number 2, p.286–296, (2011)
Improvement of porphyrins for G-quadruplex DNA targeting.,
, Biochimie, Volume 93, Number 8, p.1310–1317, (2011)
Noninvasive visualization and quantification of tumor $\alpha$V$\beta$3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4.,
, Nucl. Med. Biol., Volume 38, Number 4, p.529–540, (2011)
Redox strategy for reversible attachment of biomolecules using bifunctional linkers.,
, Chem. Commun. (Cambridge, United Kingdom), Volume 47, Number 12, p.3565–3567, (2011)
Synthesis of Glycocyclopeptides by Click Chemistry and Inhibition Assays with Lectins.,
, J. Carbohydr. Chem., Volume 30, Number 7-9, p.458–468, (2011)
Targeted delivery of a proapoptotic peptide to tumors in vivo.,
, J. Drug Target., Volume 19, Number 7, p.582–588, (2011)
Tethered Bilayer Lipid Membranes on Mixed Self-Assembled Monolayers of a Novel Anchoring Thiol: Impact of the Anchoring Thiol Density on Bilayer Formation.,
, Langmuir, Volume 27, Number 23, p.14317–14328, (2011)
The Use of a Peptidic Scaffold for the Formation of Stable Guanine Tetrads: Control of a H-bonded Pattern in Water.,
, Chem. - A Eur. J., Volume 17, Number 21, p.5791–5795, S5791/1–S5791/21, (2011)
Versatile Introduction of Azido Moiety into Oligonucleotides through Diazo Transfer Reaction.,
, Org. Lett., Volume 13, Number 20, p.5672–5675, (2011)
X-Ray Structure of the Key Synthetic Intermediate of a Cancer-Related Sialyl-Tn Antigen Analogue.,
, J. Chem. Crystallogr., Volume 41, Number 2, p.204–208, (2011)
Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.,
, Org. Biomol. Chem., Volume 8, Number 22, p.5133–5138, (2010)
Cell adhesion through clustered ligand on fluid supported lipid bilayers.,
, Org. Biomol. Chem., Volume 8, Number 7, p.1531–1534, (2010)
Electrochemically Controlled Adsorption of Fc-Functionalized Polymers on $\beta$-CD-Modified Self-Assembled Monolayers.,
, Langmuir, Volume 26, Number 17, p.13976–13986, (2010)
Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity.,
, PLoS One, Volume 5, Number 6, p.No pp. given, (2010)
Molecular engineering of biomolecules for nanobio-sciences.,
, Int. J. Nanotechnol., Volume 7, Number 4/5/6/7/8, p.738–752, (2010)
Oligonucleotide Sequential Bis-Conjugation via Click-Oxime and Click-Huisgen Procedures.,
, J. Org. Chem., Volume 75, Number 11, p.3927–3930, (2010)
RGD-cyclam conjugate: Synthesis and potential application for positron emission tomography.,
, Bioorg. Med. Chem. Lett., Volume 20, Number 18, p.5422–5425, (2010)
Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells.,
, J. Am. Chem. Soc., Volume 132, Number 19, p.6800–6808, (2010)
Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies.,
, Chem. - A Eur. J., Volume 16, Number 20, p.6106–6114, S6106/1–S6106/16, (2010)
Unlimited growth of host-guest multilayer films based on functionalized neutral polymers.,
, Soft Matter, Volume 6, Number 16, p.3747–3750, (2010)
Antitumor activity of a self-adjuvanting glyco-lipopeptide vaccine bearing B cell, CD4+ and CD8+ T cell epitopes.,
, Cancer Immunol. Immunother., Volume 58, Number 2, p.187–200, (2009)
Artificial enzyme-based biosensors.,
, New J. Chem., Volume 33, Number 5, p.939–946, (2009)
Biomolecular assembly by iterative oxime ligations.,
, Bioorg. Med. Chem. Lett., Volume 19, Number 14, p.3880–3883, (2009)
Chemical synthesis, DNA incorporation and biological study of a new photo-cleavable 2'-deoxyadenosine mimic.,
, Nucleic Acids Res., Volume 37, Number 16, p.5237–5245, (2009)
Clustering and Internalization of Integrin $\alpha$v$\beta$3 With a Tetrameric RGD-synthetic Peptide.,
, Mol. Ther., Volume 17, Number 5, p.837–843, (2009)
Design and synthesis of novel hybrid metal complex-DNA conjugates: Key building blocks for multimetallic linear DNA nanoarrays.,
, Org. Biomol. Chem., Volume 7, Number 13, p.2729–2737, (2009)
Drug development in oncology assisted by noninvasive optical imaging.,
, Int. J. Pharm., Volume 379, Number 2, p.309–316, (2009)
Efficient conjugation of oligonucleotides through aromatic oxime formation.,
, Bioorg. Med. Chem. Lett., Volume 19, Number 23, p.6534–6537, (2009)
Functionalization of the A ring of pyridoacridine as a route toward greater structural diversity. Synthesis of an octacyclic analogue of eilatin.,
, Bioorg. Med. Chem. Lett., Volume 19, Number 16, p.4836–4838, (2009)
A Gadolinium-Binding Cyclodecapeptide with a Large High-Field Relaxivity Involving Second-Sphere Water.,
, Chem. - A Eur. J., Volume 15, Number 29, p.7083–7093, S7083/1–S7083/8, (2009)
Highly efficient cell adhesion on beads functionalized with clustered peptide ligands.,
, Org. Biomol. Chem., Volume 7, Number 20, p.4159–4162, (2009)
Oligonucleotide duplexes with tethered photoreactive ruthenium(II) complexes: influence of the ligands and their linker on the photoinduced electron transfer and crosslinking processes of the two strands.,
, Eur. J. Inorg. Chem., Number 4, p.524–532, (2009)
One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations.,
, Angew. Chemie, Int. Ed., Volume 48, Number 14, p.2576–2579, (2009)
Phenolic oxime oligomers inhibit Alzheimer's amyloid fibril formation and disaggregate fibrils in vitro.,
, ChemBioChem, Volume 10, Number 8, p.1325–1329, (2009)
Synthesis and Biological Evaluation of Clicked Curcumin and Clicked KLVFFA Conjugates as Inhibitors of $\beta$-Amyloid Fibril Formation.,
, Bioconjug. Chem., Volume 20, Number 11, p.2123–2132, (2009)
Synthesis and evaluation of fused bispyrimidinoacridines as novel pentacyclic analogues of quadruplex-binder BRACO-19.,
, Org. Biomol. Chem., Volume 7, Number 24, p.5219–5228, (2009)
Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells.,
, Org. Biomol. Chem., Volume 7, Number 2, p.221–224, (2009)
1-Ethoxyethylidene, a New Group for the Stepwise SPPS of Aminooxyacetic Acid Containing Peptides.,
, J. Org. Chem., Volume 73, Number 3, p.983–991, (2008)
Chemical and Biological Evaluations of an 111In-Labeled RGD-Peptide Targeting Integrin Alpha(V) Beta(3) in a Preclinical Tumor Model.,
, Cancer Biother. Radiopharm., Volume 23, Number 6, p.691–700, (2008)
Concise Synthesis of 2-Amino-4(3H)-quinazolinones from Simple (Hetero)aromatic Amines.,
, J. Org. Chem., Volume 73, Number 6, p.2473–2475, (2008)
Cyclic peptides bearing a side-chain tail: a tool to model the structure and reactivity of protein zinc sites.,
, Angew. Chemie, Int. Ed., Volume 47, Number 36, p.6888–6891, (2008)
A cyclodecapeptide ligand to vitamin B12.,
, Org. Biomol. Chem., Volume 6, Number 22, p.4134–4141, (2008)
A fully solid-phase synthesis of biotinylated glycoclusters.,
, Open Glycosci., Volume 1, p.1–7, (2008)
High-throughput identification of combinatorial ligands for DNA delivery in cell culture.,
, AIP Conf. Proc., Volume 1062, Number DNA-Based Nanodevices, p.73–88, (2008)
A multimeric quinacrine conjugate as a potential inhibitor of Alzheimer's $\beta$-amyloid fibril formation.,
, ChemBioChem, Volume 9, Number 6, p.952–963, (2008)
Nanomolar heparin detection with an artificial enzyme.,
, ChemBioChem, Volume 9, Number 18, p.2950–2953, (2008)
NMR and Theoretical Calculations: A Unified View of the Cis/Trans Isomerization of 2-Substituted Thiazolidine Containing Peptides.,
, J. Phys. Chem. B, Volume 112, Number 32, p.9975–9981, (2008)
A novel conformationally constrained parallel G quadruplex.,
, ChemBioChem, Volume 9, Number 16, p.2588–2591, (2008)
Oxime-based synthesis of new chromogenic and fluorogenic oligosaccharides.,
, European J. Org. Chem., Number 32, p.5383–5386, (2008)
Promotion of sugar-lectin recognition through the multiple sugar presentation offered by regioselectively addressable functionalized templates (RAFT): a QCM-D and SPR study.,
, Org. Biomol. Chem., Volume 6, Number 6, p.1114–1122, (2008)
RAFT Nano-constructs: surfing to biological applications.,
, J. Pept. Sci., Volume 14, Number 2, p.224–240, (2008)
Randomized Combinatorial Library of Hetero-glyco-clusters (hGC).,
, J. Comb. Chem., Volume 10, Number 3, p.368–371, (2008)
Surface patterning of (bio)molecules onto the inner wall of fused-silica capillary tubes.,
, Lab Chip, Volume 8, Number 12, p.2161–2163, (2008)
Synthesis and biological characterization of targeted pro-apoptotic peptide.,
, ChemBioChem, Volume 9, Number 14, p.2326–2332, (2008)
Synthesis of N-acridinyl-N'-alkylguanidines: Dramatic influence of amine to guanidine replacement on the physicochemical properties.,
, Bioorg. Med. Chem. Lett., Volume 18, Number 17, p.4779–4782, (2008)
Activatable probes for non-invasive small animal fluorescence imaging.,
, Nucl. Instruments Methods Phys. Res. Sect. A Accel. Spectrometers, Detect. Assoc. Equip., Volume 571, Number 1+2, p.165–168, (2007)
Aldehydic Oligonucleotide: A Key Intermediate for the Preparation of Oligonucleotide Conjugates Through Oxime Bond Formation.,
, Nucleosides. Nucleotides Nucleic Acids, Volume 26, Number 8-9, p.883–887, (2007)
Designed amyloid $\beta$ peptide fibril-a tool for high-throughput screening of fibril inhibitors.,
, ChemMedChem, Volume 2, Number 11, p.1613–1623, (2007)
Efficient Surface Patterning of Oligonucleotides Inside a Glass Capillary through Oxime Bond Formation.,
, Bioconjug. Chem., Volume 18, Number 3, p.671–676, (2007)
Fluorescent ADP Sensing in Physiological Conditions Based on Cooperative Inhibition of a Miniature Esterase.,
, J. Am. Chem. Soc., Volume 129, Number 16, p.4884–4885, (2007)
In vivo noninvasive optical imaging of receptor-mediated RGD internalization using self-quenched Cy5-labeled RAFT-c(-RGDfK-)4.,
, Mol. Imaging, Volume 6, Number 1, p.43–55, (2007)
New Solid Support for the Synthesis of 3'-Oligonucleotide Conjugates through Glyoxylic Oxime Bond Formation.,
, Org. Lett., Volume 9, Number 2, p.219–222, (2007)
Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction.,
, Biochem. J., Volume 408, Number 3, p.363–373, (2007)
Cyclodecapeptides to mimic the radical site of tyrosyl-containing proteins.,
, J. Pept. Sci., Volume 12, Number 9, p.612–619, (2006)
Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template.,
, Langmuir, Volume 22, Number 19, p.8134–8143, (2006)
Reactivity of Pyrido[4,3,2-kl]acridines: Regioselective Formation of 6-Substituted Derivatives.,
, J. Org. Chem., Volume 69, Number 23, p.8144–8147, (2004)