Département de chimie moléculaire

Noninvasive visualization and quantification of tumor $\alpha$V$\beta$3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Galibert Mathieu, Boturyn Didier, Coll Jean-Luc, Fukumura Toshimitsu, Saga Tsuneo, Dumy Pascal, and Fujibayashi Yasuhisa. , Nucl. Med. Biol., Volume 38, Number 4, p.529–540, (2011)

One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations., Galibert, Mathieu, Dumy Pascal, and Boturyn Didier , Angew. Chemie, Int. Ed., Volume 48, Number 14, p.2576–2579, (2009)

Oxime Ligation: A Chemoselective Click-Type Reaction for Accessing Multifunctional Biomolecular Constructs., Ulrich, Sebastien, Boturyn Didier, Marra Alberto, Renaudet Olivier, and Dumy Pascal , Chem. - A Eur. J., Volume 20, Number 1, p.34–41, (2014)

PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of 64Cu-cyclam-RAFT-c(-RGDfK-)4in vivo., Jin, Zhao-hui, Furukawa Takako, Sogawa Chizuru, Claron Michael, Aung Winn, Tsuji Atsushi B., Wakizaka Hidekatsu, Zhang Ming-Rong, Boturyn Didier, Dumy Pascal, et al. , Eur. J. Pharm. Biopharm., Volume 86, Number 3, p.478–486, (2014)

"Polymultivalent" Polymer-Peptide Cluster Conjugates for an Enhanced Targeting of Cells Expressing $\alpha$v$\beta$3 Integrins., Duret, Damien, Grassin Adrien, Henry Maxime, Jacquet Thibault, Thoreau Fabien, Denis-Quanquin Sandrine, Coll Jean-Luc, Boturyn Didier, Favier Arnaud, and Charreyre Marie-Therese. , Bioconjug. Chem., Volume 28, Number 9, p.2241–2245, (2017)

Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Claron Michael, Boturyn Didier, Coll Jean-Luc, Fukumura Toshimitsu, Fujibayashi Yasuhisa, Dumy Pascal, and Saga Tsuneo. , Angiogenesis, Volume 15, Number 4, p.569–580, (2012)

Positron emission tomography of cerebral angiogenesis and TSPO expression in a mouse model of chronic hypoxia., Kanno, Iwao, Seki Chie, Takuwa Hiroyuki, Jin Zhao-hui, Boturyn Didier, Dumy Pascal, Furukawa Takako, Saga Tsuneo, Ito Hiroshi, and Masamoto Kazuto. , J. Cereb. Blood Flow Metab., Volume 38, Number 4, p.687–696, (2018)

Preparation of dihydropyrene derivatives and their uses., Royal, Guy, Cobo Saioa, Saint-Aman Eric, Josserand Veronique, and Boturyn Didier , (2016)

Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer, Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Sugyo Aya, Obara Satoshi, Wakizaka Hidekatsu, Nagatsu Kotaro, Hu Kuan, Zhang Ming-Rong, Dumy Pascal, et al. , Clinical Cancer Research, 09/2020, Volume 26, Issue 23, p.6230-6241, (2020)

RAFT Nano-constructs: surfing to biological applications., Boturyn, Didier, Defrancq Eric, Dolphin Gunnar T., Garcia Julian, Labbe Pierre, Renaudet Olivier, and Dumy Pascal , J. Pept. Sci., Volume 14, Number 2, p.224–240, (2008)

Ratiometric Luminescence Detection of Copper(I) by a Resonant System Comprising Two Antenna/Lanthanide Pairs, Cepeda, Celine, Denisov Sergey A., Boturyn Didier, McClenaghan Nathan D., and Sénèque Olivier , Inorganic Chemistry, 11/2021, Volume 60, p.17426−17434, (2021)

Redox strategy for reversible attachment of biomolecules using bifunctional linkers., Dubacheva, Galina V., Galibert Mathieu, Guerente Liliane, Dumy Pascal, Boturyn Didier, and Labbe Pierre , Chem. Commun. (Cambridge, United Kingdom), Volume 47, Number 12, p.3565–3567, (2011)

Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template., Devillers, Charles H., Boturyn Didier, Bucher Christophe, Dumy Pascal, Labbe Pierre, Moutet Jean-Claude, Royal Guy, and Saint-Aman Eric , Langmuir, Volume 22, Number 19, p.8134–8143, (2006)

Redox-driven host-guest interactions allow the controlled release of captured cells on RGD-functionalized surfaces., Thakar, Dhruv, Guerente Liliane, Claron Michael, Wenk Christiane H. F., Dejeu Jérôme, Dumy Pascal, Labbe Pierre, and Boturyn Didier , ChemBioChem, Volume 15, Number 3, p.377–381, (2014)

Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin $\alpha$v$\beta$3 targeting using single photon emission computed tomography and optical imaging., Briat, Arnaud, Wenk Christiane H. F., Ahmadi Mitra, Claron Michael, Boturyn Didier, Josserand Veronique, Dumy Pascal, Fagret Daniel, Coll Jean-Luc, Ghezzi Catherine, et al. , Cancer Sci., Volume 103, Number 6, p.1105–1110, (2012)

RGD-cyclam conjugate: Synthesis and potential application for positron emission tomography., Galibert, Mathieu, Jin Zhao-hui, Furukawa Takako, Fukumura Toshimitsu, Saga Tsuneo, Fujibayashi Yasuhisa, Dumy Pascal, and Boturyn Didier , Bioorg. Med. Chem. Lett., Volume 20, Number 18, p.5422–5425, (2010)

Synthesis and Biological Characterization of Monomeric and Tetrameric RGD-Cryptophycin Conjugates, Borbély, Adina, Thoreau Fabien, Figueras Eduard, Kadri Malika, Coll Jean-Luc, Boturyn Didier, and Sewald Norbert , Chemistry – A European Journal, 01/2020, Volume 26, p.2602 – 2605, (2020)

Synthesis and biological characterization of targeted pro-apoptotic peptide., Foillard, Stephanie, Jin Zhao-hui, Garanger Elisabeth, Boturyn Didier, Favrot Marie-Christine, Coll Jean-Luc, and Dumy Pascal , ChemBioChem, Volume 9, Number 14, p.2326–2332, (2008)

Synthesis and photophysical studies of a multivalent photoreactive RuII-calix[4]arene complex bearing RGD-containing cyclopentapeptides., Kajouj, Sofia, Marcelis Lionel, Mattiuzzi Alice, Grassin Adrien, Dufour Damien, Van Antwerpen Pierre, Boturyn Didier, Defrancq Eric, Surin Mathieu, De Winter Julien, et al. , Beilstein J. Org. Chem., Volume 14, p.1758–1768, (2018)

Synthesis by native chemical ligation and characterization of the scorpion toxin AmmTx3, Zoukimian, Claude, Meudal Hervé, De Waard Stephan, Ouares Karima Ait, Nicolas Sébastien, Canepari Marco, Béroud Rémy, Landon Céline, De Waard Michel, and Boturyn Didier , Bioorganic & Medicinal Chemistry, Volume 27, p.247 - 253, (2019)

Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model., Karageorgis, Anastassia, Claron Michael, Juge Romain, Aspord Caroline, Thoreau Fabien, Leloup Claire, Kucharczak Jerome, Plumas Joel, Henry Maxime, Hurbin Amandine, et al. , Mol. Ther., Volume 25, Number 2, p.534–546, (2017)

Targeted delivery of a proapoptotic peptide to tumors in vivo., Dufort, Sandrine, Sancey Lucie, Hurbin Amandine, Foillard Steephanie, Boturyn Didier, Dumy Pascal, and Coll Jean-Luc. , J. Drug Target., Volume 19, Number 7, p.582–588, (2011)

Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells., Foillard, Stephanie, Sancey Lucie, Coll Jean-Luc, Boturyn Didier, and Dumy Pascal , Org. Biomol. Chem., Volume 7, Number 2, p.221–224, (2009)

Targeted radionuclide therapy with RAFT-RGD radiolabelled with 90Y or 177Lu in a mouse model of $\alpha$v$\beta$3-expressing tumours., Bozon-Petitprin, A, Bacot S, Gauchez A S., Ahmadi M, Bourre J C., Marti-Batlle D, Perret P, Broisat A, Riou L M., Claron M, et al. , Eur. J. Nucl. Med. Mol. Imaging, Volume 42, Number 2, p.252–263, (2015)

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model., Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Sugyo Aya, Yoshii Yukie, Nagatsu Kotaro, Zhang Ming-Rong, Fujibayashi Yasuhisa, Dumy Pascal, Boturyn Didier, et al. , EJNMMI Res., Volume 8, Number 1, p.1–10, (2018)

Using Native Chemical Ligation for Site-specific Synthesis of Hetero-bis-lanthanide Peptide Conjugates: Application to Ratiometric Visible or Near-infrared Detection of Zn2+, Cepeda, Celine, Raibaut Laurent, Fremy Guillaume, Eliseeva Svetlana V., Romieu Anthony, Pécaut Jacques, Boturyn Didier, Petoud Stephane, and Sénèque Olivier , Chemistry – A European Journal, 07/2020, Volume 26, p.13476-13483, (2020)