Département de chimie moléculaire

Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Claron Michael, Boturyn Didier, Coll Jean-Luc, Fukumura Toshimitsu, Fujibayashi Yasuhisa, Dumy Pascal, and Saga Tsuneo. , Angiogenesis, Volume 15, Number 4, p.569–580, (2012)

Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin $\alpha$v$\beta$3 targeting using single photon emission computed tomography and optical imaging., Briat, Arnaud, Wenk Christiane H. F., Ahmadi Mitra, Claron Michael, Boturyn Didier, Josserand Veronique, Dumy Pascal, Fagret Daniel, Coll Jean-Luc, Ghezzi Catherine, et al. , Cancer Sci., Volume 103, Number 6, p.1105–1110, (2012)

Access to Biomolecular Assemblies through One-Pot Triple Orthogonal Chemoselective Ligations., Galibert, Mathieu, Renaudet Olivier, Dumy Pascal, and Boturyn Didier , Angew. Chemie, Int. Ed., Volume 50, Number 8, p.1901–1904, S1901/1–S1901/32, (2011)

Noninvasive visualization and quantification of tumor $\alpha$V$\beta$3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Galibert Mathieu, Boturyn Didier, Coll Jean-Luc, Fukumura Toshimitsu, Saga Tsuneo, Dumy Pascal, and Fujibayashi Yasuhisa. , Nucl. Med. Biol., Volume 38, Number 4, p.529–540, (2011)

Redox strategy for reversible attachment of biomolecules using bifunctional linkers., Dubacheva, Galina V., Galibert Mathieu, Guerente Liliane, Dumy Pascal, Boturyn Didier, and Labbe Pierre , Chem. Commun. (Cambridge, United Kingdom), Volume 47, Number 12, p.3565–3567, (2011)

Targeted delivery of a proapoptotic peptide to tumors in vivo., Dufort, Sandrine, Sancey Lucie, Hurbin Amandine, Foillard Steephanie, Boturyn Didier, Dumy Pascal, and Coll Jean-Luc. , J. Drug Target., Volume 19, Number 7, p.582–588, (2011)

Application of click-click chemistry to the synthesis of new multivalent RGD conjugates., Galibert, Mathieu, Sancey Lucie, Renaudet Olivier, Coll Jean-Luc, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 8, Number 22, p.5133–5138, (2010)

Cell adhesion through clustered ligand on fluid supported lipid bilayers., Sandrin, Ludivine, Guerente Liliane, Bernstein Amandine, Basit Hajra, Labbe Pierre, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 8, Number 7, p.1531–1534, (2010)

Molecular engineering of biomolecules for nanobio-sciences., Renaudet, Olivier, Garcia Julian, Boturyn Didier, Spinelli Nicolas, Defrancq Eric, Labbe Pierre, and Dumy Pascal , Int. J. Nanotechnol., Volume 7, Number 4/5/6/7/8, p.738–752, (2010)

Non-invasive tools for detecting vulnerable atherosclerotic plaques., Fagret, Daniel, Ghezzi Catherine, Dumy Pascal, Riou Laurent, and Boturyn Didier , (2010)

RGD-cyclam conjugate: Synthesis and potential application for positron emission tomography., Galibert, Mathieu, Jin Zhao-hui, Furukawa Takako, Fukumura Toshimitsu, Saga Tsuneo, Fujibayashi Yasuhisa, Dumy Pascal, and Boturyn Didier , Bioorg. Med. Chem. Lett., Volume 20, Number 18, p.5422–5425, (2010)

Biomolecular assembly by iterative oxime ligations., Renaudet, Olivier, Boturyn Didier, and Dumy Pascal , Bioorg. Med. Chem. Lett., Volume 19, Number 14, p.3880–3883, (2009)

Clustering and Internalization of Integrin $\alpha$v$\beta$3 With a Tetrameric RGD-synthetic Peptide., Sancey, Lucie, Garanger Elisabeth, Foillard Stephanie, Schoehn Guy, Hurbin Amandine, Albiges-Rizo Corinne, Boturyn Didier, Souchier Catherine, Grichine Alexei, Dumy Pascal, et al. , Mol. Ther., Volume 17, Number 5, p.837–843, (2009)

Drug development in oncology assisted by noninvasive optical imaging., Sancey, L, Dufort S, Josserand V, Keramidas M, Righini C, Rome C, Faure A.-C., Foillard S, Roux S, Boturyn Didier, et al. , Int. J. Pharm., Volume 379, Number 2, p.309–316, (2009)

A Gadolinium-Binding Cyclodecapeptide with a Large High-Field Relaxivity Involving Second-Sphere Water., Bonnet, Celia S., Fries Pascal H., Crouzy Serge, Seneque Olivier, Cisnetti Federico, Boturyn Didier, Dumy Pascal, and Delangle Pascale. , Chem. - A Eur. J., Volume 15, Number 29, p.7083–7093, S7083/1–S7083/8, (2009)

Highly efficient cell adhesion on beads functionalized with clustered peptide ligands., Foillard, Stephanie, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 7, Number 20, p.4159–4162, (2009)

One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations., Galibert, Mathieu, Dumy Pascal, and Boturyn Didier , Angew. Chemie, Int. Ed., Volume 48, Number 14, p.2576–2579, (2009)

Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells., Foillard, Stephanie, Sancey Lucie, Coll Jean-Luc, Boturyn Didier, and Dumy Pascal , Org. Biomol. Chem., Volume 7, Number 2, p.221–224, (2009)

1-Ethoxyethylidene, a New Group for the Stepwise SPPS of Aminooxyacetic Acid Containing Peptides., Foillard, Stephanie, Rasmussen Martin Ohsten, Razkin Jesus, Boturyn Didier, and Dumy Pascal , J. Org. Chem., Volume 73, Number 3, p.983–991, (2008)

Chemical and Biological Evaluations of an 111In-Labeled RGD-Peptide Targeting Integrin Alpha(V) Beta(3) in a Preclinical Tumor Model., Ahmadi, Mitra, Sancey Lucie, Briat Arnaud, Riou Laurent, Boturyn Didier, Dumy Pascal, Fagret Daniel, Ghezzi Catherine, and Vuillez Jean-Philippe. , Cancer Biother. Radiopharm., Volume 23, Number 6, p.691–700, (2008)

RAFT Nano-constructs: surfing to biological applications., Boturyn, Didier, Defrancq Eric, Dolphin Gunnar T., Garcia Julian, Labbe Pierre, Renaudet Olivier, and Dumy Pascal , J. Pept. Sci., Volume 14, Number 2, p.224–240, (2008)

Synthesis and biological characterization of targeted pro-apoptotic peptide., Foillard, Stephanie, Jin Zhao-hui, Garanger Elisabeth, Boturyn Didier, Favrot Marie-Christine, Coll Jean-Luc, and Dumy Pascal , ChemBioChem, Volume 9, Number 14, p.2326–2332, (2008)

Activatable probes for non-invasive small animal fluorescence imaging., Texier, Isabelle, Razkin Jesus, Josserand Veronique, Boturyn Didier, Dumy Pascal, Coll Jean-Luc, and Rizo Philippe. , Nucl. Instruments Methods Phys. Res. Sect. A Accel. Spectrometers, Detect. Assoc. Equip., Volume 571, Number 1+2, p.165–168, (2007)

In vivo noninvasive optical imaging of receptor-mediated RGD internalization using self-quenched Cy5-labeled RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Razkin Jesus, Josserand Veronique, Boturyn Didier, Grichine Alexei, Texier Isabelle, Favrot Marie-Christine, Dumy Pascal, and Coll Jean-Luc. , Mol. Imaging, Volume 6, Number 1, p.43–55, (2007)

Cyclodecapeptides to mimic the radical site of tyrosyl-containing proteins., Hossain, Mohammed Akhter, Thomas Fabrice, Hamman Sylvain, Saint-Aman Eric, Boturyn Didier, Dumy Pascal, and Pierre Jean-Louis. , J. Pept. Sci., Volume 12, Number 9, p.612–619, (2006)

Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template., Devillers, Charles H., Boturyn Didier, Bucher Christophe, Dumy Pascal, Labbe Pierre, Moutet Jean-Claude, Royal Guy, and Saint-Aman Eric , Langmuir, Volume 22, Number 19, p.8134–8143, (2006)