Département de chimie moléculaire

Oligonucleotide duplexes with tethered photoreactive ruthenium(II) complexes: influence of the ligands and their linker on the photoinduced electron transfer and crosslinking processes of the two strands., Deroo, Stephanie, Le Gac Stephane, Ghosh Sumana, Villien Mathilde, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, Dumy Pascal, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Number 4, p.524–532, (2009)

Photo-reactive RuII-oligonucleotide conjugates: influence of an intercalating ligand on the inter- and intra-strand photo-ligation processes., Le Gac, Stephane, Foucart Martin, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Dalt. Trans., Volume 39, Number 40, p.9672–9683, (2010)

A photoreactive ruthenium(II) complex tethered to a guanine-containing oligonucleotide: A biomolecular tool that behaves as a "Seppuku Molecule"., Le Gac, Stephane, Rickling Stephane, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Angew. Chemie, Int. Ed., Volume 48, Number 6, p.1122–1125, (2009)

Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53., Reschner, A, Bontems S, Le Gac Stephane, Lambermont J, Marcelis L, Defrancq Eric, Hubert P, Moucheron C, A De Mesmaeker Kirsch-, Raes M, et al. , Gene Ther., Volume 20, Number 4, p.435–443, (2013)

What Are the Parameters Controlling Inter- vs. Intra-Strand DNA Photodamage with Ru-TAP Oligonucleotides?., Le Gac, Stephane, Surin Mathieu, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Volume 2013, Number 2, p.208–216, (2013)