Département de chimie moléculaire

Multivalent glyco(cyclo)peptides., M Galan, Carmen, Dumy Pascal, and Renaudet Olivier , Chem. Soc. Rev., Volume 42, Number 11, p.4599–4612, (2013)

A multimeric quinacrine conjugate as a potential inhibitor of Alzheimer's $\beta$-amyloid fibril formation., Dolphin, Gunnar T., Chierici Sabine, Ouberai Myriam, Dumy Pascal, and Garcia Julian. , ChemBioChem, Volume 9, Number 6, p.952–963, (2008)

Multilayer assemblies of polyelectrolyte-gold nanoparticles for the electrocatalytic oxidation and detection of arsenic(III)., Thotiyl, M M. Ottakam, Basit Hajra, Sanchez Julio A., Goyer Cedric, Guerente Liliane, Dumy Pascal, Sampath S, Labbe Pierre, and Moutet Jean-Claude , J. Colloid Interface Sci., Volume 383, Number 1, p.130–139, (2012)

Molecular engineering of biomolecules for nanobio-sciences., Renaudet, Olivier, Garcia Julian, Boturyn Didier, Spinelli Nicolas, Defrancq Eric, Labbe Pierre, and Dumy Pascal , Int. J. Nanotechnol., Volume 7, Number 4/5/6/7/8, p.738–752, (2010)

Micro-positron emission tomography/contrast-enhanced computed tomography imaging of orthotopic pancreatic tumor-bearing mice using the $\alpha$v$\beta$3 integrin tracer 64Cu-labeled cyclam-RAFT-c(-RGDfK-)4., Aung, Winn, Jin Zhao-hui, Furukawa Takako, Claron Michael, Boturyn Didier, Sogawa Chizuru, Tsuji Atsushi B., Wakizaka Hidekatsu, Fukumura Toshimitsu, Fujibayashi Yasuhisa, et al. , Mol. Imaging, Volume 12, Number 6, p.376–387, (2013)

Linear and branched glyco-lipopeptide vaccines follow distinct cross-presentation pathways and generate different magnitudes of antitumor immunity., Renaudet, Olivier, Dasgupta Gargi, Bettahi Ilham, Shi Alda, Nesburn Anthony B., Dumy Pascal, and BenMohamed Lbachir. , PLoS One, Volume 5, Number 6, p.No pp. given, (2010)

Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate., Wenk, Christiane H. F., Josserand Veronique, Dumy Pascal, Coll Jean-Luc, and Boturyn Didier , Org. Biomol. Chem., Volume 11, Number 3, p.448–452, (2013)

Influence of Pre-organised Architecture on Cell Adhesion by Using Multivalent RGD Compounds., Grassin, Adrien, Jourdan Muriel, Dumy Pascal, and Boturyn Didier , ChemBioChem, Volume 17, Number 6, p.515–520, (2016)

In vivo noninvasive optical imaging of receptor-mediated RGD internalization using self-quenched Cy5-labeled RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Razkin Jesus, Josserand Veronique, Boturyn Didier, Grichine Alexei, Texier Isabelle, Favrot Marie-Christine, Dumy Pascal, and Coll Jean-Luc. , Mol. Imaging, Volume 6, Number 1, p.43–55, (2007)

In vivo molecular imaging of atherosclerotic lesions in ApoE-/- mice using VCAM-1-specific, 99Tc-labeled peptidic sequences., Dimastromatteo, Julien, Broisat Alexis, Perret Pascale, Ahmadi Mitra, Boturyn Didier, Dumy Pascal, Fagret Daniel, Riou Laurent M., and Ghezzi Catherine. , J. Nucl. Med., Volume 54, Number 8, p.1442–1449, (2013)

Improvement of porphyrins for G-quadruplex DNA targeting., Romera, Carmen, Bombarde Oriane, Bonnet Romaric, Gomez Dennis, Dumy Pascal, Calsou Patrick, Gwan Jean-Fang, Lin Jung-Hsin, Defrancq Eric, and Pratviel Genevieve. , Biochimie, Volume 93, Number 8, p.1310–1317, (2011)

High-throughput identification of combinatorial ligands for DNA delivery in cell culture., Svahn, Mathias G., Rabe Kersten S., Barger Geoffrey, El-Andaloussi Samir, Simonson Oscar E., Didier Boturyn, Olivier Renaudet, Dumy Pascal, Branden Lars J., Niemeyer Christof M., et al. , AIP Conf. Proc., Volume 1062, Number DNA-Based Nanodevices, p.73–88, (2008)

Highly efficient cell adhesion on beads functionalized with clustered peptide ligands., Foillard, Stephanie, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 7, Number 20, p.4159–4162, (2009)

High Affinity Glycodendrimers for the Lectin LecB from Pseudomonas aeruginosa., Berthet, Nathalie, Thomas Baptiste, Bossu Isabelle, Dufour Emilie, Gillon Emilie, Garcia Julian, Spinelli Nicolas, Imberty Anne, Dumy Pascal, and Renaudet Olivier , Bioconjug. Chem., Volume 24, Number 9, p.1598–1611, (2013)

Hepatocyte Targeting and Intracellular Copper Chelation by a Thiol-Containing Glycocyclopeptide., Pujol, Anais M., Cuillel Martine, Renaudet Olivier, Lebrun Colette, Charbonnier Peggy, Cassio Doris, Gateau Christelle, Dumy Pascal, Mintz Elisabeth, and Delangle Pascale. , J. Am. Chem. Soc., Volume 133, Number 2, p.286–296, (2011)

Glycoside and peptide clustering around the octasilsesquioxane scaffold via photoinduced free-radical thiol-ene coupling. The observation of a striking glycoside cluster effect., Conte, Mauro Lo, Staderini Samuele, Chambery Angela, Berthet Nathalie, Dumy Pascal, Renaudet Olivier, Marra Alberto, and Dondoni Alessandro. , Org. Biomol. Chem., Volume 10, Number 16, p.3269–3277, (2012)

A Gadolinium-Binding Cyclodecapeptide with a Large High-Field Relaxivity Involving Second-Sphere Water., Bonnet, Celia S., Fries Pascal H., Crouzy Serge, Seneque Olivier, Cisnetti Federico, Boturyn Didier, Dumy Pascal, and Delangle Pascale. , Chem. - A Eur. J., Volume 15, Number 29, p.7083–7093, S7083/1–S7083/8, (2009)

Functionalization of the A ring of pyridoacridine as a route toward greater structural diversity. Synthesis of an octacyclic analogue of eilatin., Bouffier, Laurent, Dinica Rodica, Debray Julien, Dumy Pascal, and Demeunynck Martine , Bioorg. Med. Chem. Lett., Volume 19, Number 16, p.4836–4838, (2009)

A fully solid-phase synthesis of biotinylated glycoclusters., Renaudet, Olivier, and Dumy Pascal , Open Glycosci., Volume 1, p.1–7, (2008)

Fluorescent molecules for surgery., Dumy, Pascal, Wenk Christiane, Claron Michael, Coll Jean-Luc, Allard Odile, and Boturyn Didier , Actual. Chim., Volume 366, p.23–28, (2012)

Fluorescent ADP Sensing in Physiological Conditions Based on Cooperative Inhibition of a Miniature Esterase., Vial, Laurent, and Dumy Pascal , J. Am. Chem. Soc., Volume 129, Number 16, p.4884–4885, (2007)

Expanding the scope of oxime ligation: facile synthesis of large cyclopeptide-based glycodendrimers., Thomas, Baptiste, Berthet Nathalie, Garcia Julian, Dumy Pascal, and Renaudet Olivier , Chem. Commun. (Cambridge, United Kingdom), Volume 49, Number 92, p.10796–10798, (2013)

Engineering of biomolecules for sensing and imaging applications., Ulrich, S, Dumy Pascal, Boturyn Didier, and Renaudet Olivier , J. Drug Deliv. Sci. Technol., Volume 23, Number 1, p.5–15, (2013)

Electrochemically Controlled Adsorption of Fc-Functionalized Polymers on $\beta$-CD-Modified Self-Assembled Monolayers., Dubacheva, Galina V., Van der Heyden Angeline, Dumy Pascal, Kaftan Oznur, Auzely Rachel, Guerente Liliane, and Labbe Pierre , Langmuir, Volume 26, Number 17, p.13976–13986, (2010)

Efficient Surface Patterning of Oligonucleotides Inside a Glass Capillary through Oxime Bond Formation., Dendane, Nabil, Hoang Antoine, Guillard Ludovic, Defrancq Eric, Vinet Francoise, and Dumy Pascal , Bioconjug. Chem., Volume 18, Number 3, p.671–676, (2007)

Efficient conjugation of oligonucleotides through aromatic oxime formation., Murat, Pierre, Spinelli Nicolas, Dumy Pascal, and Defrancq Eric , Bioorg. Med. Chem. Lett., Volume 19, Number 23, p.6534–6537, (2009)

Drug development in oncology assisted by noninvasive optical imaging., Sancey, L, Dufort S, Josserand V, Keramidas M, Righini C, Rome C, Faure A.-C., Foillard S, Roux S, Boturyn Didier, et al. , Int. J. Pharm., Volume 379, Number 2, p.309–316, (2009)

Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine-thymine mismatch., Jourdan, Muriel, Granzhan Anton, Guillot Régis, Dumy Pascal, and Teulade-Fichou Marie-Paule. , Nucleic Acids Res., Volume 40, Number 11, p.5115–5128, (2012)

Designed amyloid $\beta$ peptide fibril-a tool for high-throughput screening of fibril inhibitors., Dolphin, Gunnar T., Ouberai Myriam, Dumy Pascal, and Garcia Julian. , ChemMedChem, Volume 2, Number 11, p.1613–1623, (2007)

Design and synthesis of novel hybrid metal complex-DNA conjugates: Key building blocks for multimetallic linear DNA nanoarrays., Ghosh, Sumana, Pignot-Paintrand Isabelle, Dumy Pascal, and Defrancq Eric , Org. Biomol. Chem., Volume 7, Number 13, p.2729–2737, (2009)

Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters., Bossu, Isabelle, Sulc Miroslav, Krenek Karel, Dufour Emilie, Garcia Julian, Berthet Nathalie, Dumy Pascal, Kren Vladimir, and Renaudet Olivier , Org. Biomol. Chem., Volume 9, Number 6, p.1948–1959, (2011)

Cyclodecapeptides to mimic the radical site of tyrosyl-containing proteins., Hossain, Mohammed Akhter, Thomas Fabrice, Hamman Sylvain, Saint-Aman Eric, Boturyn Didier, Dumy Pascal, and Pierre Jean-Louis. , J. Pept. Sci., Volume 12, Number 9, p.612–619, (2006)

A cyclodecapeptide ligand to vitamin B12., Dulery, Vincent, Uhlich Nicolas A., Maillard Noelie, Fluxa Viviana S., Garcia Julian, Dumy Pascal, Renaudet Olivier, Reymond Jean-Louis, and Darbre Tamis. , Org. Biomol. Chem., Volume 6, Number 22, p.4134–4141, (2008)

Cyclic peptides bearing a side-chain tail: a tool to model the structure and reactivity of protein zinc sites., Seneque, Olivier, Bourles Emilie, Lebrun Vincent, Bonnet Estelle, Dumy Pascal, and Latour Jean-Marc. , Angew. Chemie, Int. Ed., Volume 47, Number 36, p.6888–6891, (2008)

Cyclic neoglycodecapeptides: how to increase their inhibitory activity and selectivity on lectin/toxin binding to a glycoprotein and cells., Andre, Sabine, Renaudet Olivier, Bossu Isabelle, Dumy Pascal, and Gabius Hans-Joachim. , J. Pept. Sci., Volume 17, Number 6, p.427–437, (2011)

Controlled Density Patterning of Tolylterpyridine-Tagged Oligonucleotides., Tuccitto, Nunzio, Giamblanco Nicoletta, Ghosh Sumana, Spampinato Valentina, Labbe Pierre, Dumy Pascal, Quici Silvio, Marletta Giovanni, Defrancq Eric, and Licciardello Antonino. , Langmuir, Volume 27, Number 14, p.8595–8599, (2011)

Concise Synthesis of 2-Amino-4(3H)-quinazolinones from Simple (Hetero)aromatic Amines., Zeghida, Walid, Debray Julien, Chierici Sabine, Dumy Pascal, and Demeunynck Martine , J. Org. Chem., Volume 73, Number 6, p.2473–2475, (2008)

Co-liposomes comprising a lipidated multivalent RGD-peptide and a cationic gemini cholesterol induce selective gene transfection in $\alpha$v$\beta$3 and $\alpha$v$\beta$5 integrin receptor-rich cancer cells., Misra, Santosh K., Kondaiah Paturu, Bhattacharya Santanu, Boturyn Didier, and Dumy Pascal , J. Mater. Chem. B Mater. Biol. Med., Volume 2, Number 35, p.5758–5767, (2014)

Clustering and Internalization of Integrin $\alpha$v$\beta$3 With a Tetrameric RGD-synthetic Peptide., Sancey, Lucie, Garanger Elisabeth, Foillard Stephanie, Schoehn Guy, Hurbin Amandine, Albiges-Rizo Corinne, Boturyn Didier, Souchier Catherine, Grichine Alexei, Dumy Pascal, et al. , Mol. Ther., Volume 17, Number 5, p.837–843, (2009)

Clicked tacrine conjugates as acetylcholinesterase and $\beta$-amyloid directed compounds., Ouberai, Myriam, Brannstrom Kristoffer, Vestling Monika, Olofsson Anders, Dumy Pascal, Chierici Sabine, and Garcia Julian. , Org. Biomol. Chem., Volume 9, Number 4, p.1140–1147, (2011)

Chemical synthesis, DNA incorporation and biological study of a new photo-cleavable 2'-deoxyadenosine mimic., Berthet, Nathalie, Crey-Desbiolles Caroline, Kotera Mitsuharu, and Dumy Pascal , Nucleic Acids Res., Volume 37, Number 16, p.5237–5245, (2009)

Chemical and Biological Evaluations of an 111In-Labeled RGD-Peptide Targeting Integrin Alpha(V) Beta(3) in a Preclinical Tumor Model., Ahmadi, Mitra, Sancey Lucie, Briat Arnaud, Riou Laurent, Boturyn Didier, Dumy Pascal, Fagret Daniel, Ghezzi Catherine, and Vuillez Jean-Philippe. , Cancer Biother. Radiopharm., Volume 23, Number 6, p.691–700, (2008)

Cell adhesion through clustered ligand on fluid supported lipid bilayers., Sandrin, Ludivine, Guerente Liliane, Bernstein Amandine, Basit Hajra, Labbe Pierre, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 8, Number 7, p.1531–1534, (2010)

Biomolecular assembly by iterative oxime ligations., Renaudet, Olivier, Boturyn Didier, and Dumy Pascal , Bioorg. Med. Chem. Lett., Volume 19, Number 14, p.3880–3883, (2009)

Artificial enzyme-based biosensors., Vial, Laurent, and Dumy Pascal , New J. Chem., Volume 33, Number 5, p.939–946, (2009)

Application of click-click chemistry to the synthesis of new multivalent RGD conjugates., Galibert, Mathieu, Sancey Lucie, Renaudet Olivier, Coll Jean-Luc, Dumy Pascal, and Boturyn Didier , Org. Biomol. Chem., Volume 8, Number 22, p.5133–5138, (2010)

Antitumor activity of a self-adjuvanting glyco-lipopeptide vaccine bearing B cell, CD4+ and CD8+ T cell epitopes., Bettahi, Ilham, Dasgupta Gargi, Renaudet Olivier, Chentoufi Aziz Alami, Zhang Xiuli, Carpenter Dale, Yoon Susan, Dumy Pascal, and BenMohamed Lbachir. , Cancer Immunol. Immunother., Volume 58, Number 2, p.187–200, (2009)

Amyloidogenesis highlighted by designed peptides forming supramolecular self-assemblies., Ouberai, Myriam, Dolphin Gunnar T., Dumy Pascal, and Garcia Julian. , Chem. Sci., Volume 2, Number 7, p.1293–1300, (2011)

Amphipol mediated surface immobilization of FhuA: a platform for label-free detection of the bacteriophage protein pb5., Basit, Hajra, K Sharma Shivaji, Van der Heyden Angeline, Gondran Chantal, Breyton Cecile, Dumy Pascal, Winnik Francoise M., and Labbe Pierre , Chem. Commun. (Cambridge, United Kingdom), Volume 48, Number 48, p.6037–6039, (2012)

$\alpha$V$\beta$3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Degardin Melissa, Sugyo Aya, Tsuji Atsushi B., Yamasaki Tomoteru, Kawamura Kazunori, Fujibayashi Yasuhisa, Zhang Ming-Rong, Boturyn Didier, et al. , Mol. Cancer Ther., Volume 15, Number 9, p.2076–2085, (2016)