Département de chimie moléculaire

Evaluation of a new biocompatible poly(N-(morpholino ethyl methacrylate))-based copolymer for the delivery of ruthenium oligonucleotides, targeting HPV16 E6 oncogene., Reschner, Anca, Shim Yong Ho, Dubois Philippe, Delvenne Philippe, Evrard Brigitte, Marcelis Lionel, Moucheron Cecile, De Mesmaeker Andree Kirsch-, Defrancq Eric, Raes Martine, et al. , J. Biomed. Nanotechnol., Volume 9, Number 8, p.1432–1440, (2013)

Highly DNA-Photoreactive Ruthenium 1,4,5,8-Tetraazaphenanthrene Complex Conjugated to the TAT Peptide: Efficient Vectorization inside HeLa Cells without Phototoxicity - The Importance of Cellular Distribution., Marcelis, Lionel, Kajouj Sofia, Ghesquiere Jonathan, Fettweis Gregory, Coupienne Isabelle, Lartia Remy, Surin Mathieu, Defrancq Eric, Piette Jacques, Moucheron Cecile, et al. , Eur. J. Inorg. Chem., Volume 2016, Number 18, p.2902–2911, (2016)

Oligonucleotide duplexes with tethered photoreactive ruthenium(II) complexes: influence of the ligands and their linker on the photoinduced electron transfer and crosslinking processes of the two strands., Deroo, Stephanie, Le Gac Stephane, Ghosh Sumana, Villien Mathilde, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, Dumy Pascal, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Number 4, p.524–532, (2009)

Oxidizing Ru(II) Complexes as Irreversible and Specific Photocrosslinking Agents of Oligonucleotide Duplexes., Ghizdavu, Liana, Pierard Frederic, Rickling Stephane, Aury Sabrina, Surin Mathieu, Beljonne David, Lazzaroni Roberto, Murat Pierre, Defrancq Eric, Moucheron Cecile, et al. , Inorg. Chem., Volume 48, Number 23, p.10988–10994, (2009)

Photocrosslinking between Peptide-Peptide or Peptide-Oligonucleotide by RuII-TAP Complexes., Ghesquiere, Jonathan, Gauthier Nicolas, De Winter Julien, Gerbaux Pascal, Moucheron Cecile, Defrancq Eric, and De Mesmaeker Andree. Kirsch- , Chem. - A Eur. J., Volume 18, Number 1, p.55–364, S355/1–S355/7, (2012)

Photo-Cross-Linking between Polymers Derivatized with Photoreactive Ruthenium-1,4,5,8-Tetraazaphenanthrene Complexes and Guanine-Containing Oligonucleotides., Deroo, Stephanie, Toncheva Veska, Defrancq Eric, Moucheron Cecile, Schacht Etienne, and De Mesmaeker Andree. Kirsch- , Biomacromolecules, Volume 8, Number 11, p.3503–3510, (2007)

Photoinduced Electron Transfer from Tryptophan to RuIITAP Complexes: The Primary Process for Photo-Cross-Linking with Oligopeptides., Rebarz, Mateusz, Ghesquiere Jonathan, Boisdenghien Arnaud, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Inorg. Chem., Volume 49, Number 23, p.10867–10874, (2010)

Photo-reactive RuII-oligonucleotide conjugates: influence of an intercalating ligand on the inter- and intra-strand photo-ligation processes., Le Gac, Stephane, Foucart Martin, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Dalt. Trans., Volume 39, Number 40, p.9672–9683, (2010)

A photoreactive ruthenium(II) complex tethered to a guanine-containing oligonucleotide: A biomolecular tool that behaves as a "Seppuku Molecule"., Le Gac, Stephane, Rickling Stephane, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Angew. Chemie, Int. Ed., Volume 48, Number 6, p.1122–1125, (2009)

A Rigid Dinuclear Ruthenium(II) Complex as an Efficient Photoactive Agent for Bridging Two Guanine Bases of a Duplex or Quadruplex Oligonucleotide., Rickling, Stephane, Ghisdavu Liana, Pierard Frederic, Gerbaux Pascal, Surin Mathieu, Murat Pierre, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Chem. - A Eur. J., Volume 16, Number 13, p.3951–3961, S3951/1–S3951/9, (2010)

Specificity of light-induced covalent adduct formation between RuII oligonucleotide conjugates and target sequences for gene silencing applications., Marcelis, Lionel, Surin Mathieu, Lartia Remy, Moucheron Cecile, Defrancq Eric, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Volume 2014, Number 19, p.3016–3022, (2014)

What Are the Parameters Controlling Inter- vs. Intra-Strand DNA Photodamage with Ru-TAP Oligonucleotides?., Le Gac, Stephane, Surin Mathieu, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Volume 2013, Number 2, p.208–216, (2013)