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Publications

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Journal Article
What Are the Parameters Controlling Inter- vs. Intra-Strand DNA Photodamage with Ru-TAP Oligonucleotides?., Le Gac, Stephane, Surin Mathieu, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Volume 2013, Number 2, p.208–216, (2013)
Versatile Introduction of Azido Moiety into Oligonucleotides through Diazo Transfer Reaction., Lartia, Remy, Murat Pierre, Dumy Pascal, and Defrancq Eric , Org. Lett., Volume 13, Number 20, p.5672–5675, (2011)
Use of T-2 toxin-immobilized amine-activated beads as an efficient affinity purification matrix for the isolation of specific IgY., Edupuganti, Soujanya Ratna, Edupuganti Om Prakash, O'Kennedy Richard, Defrancq Eric, and Boullanger Stephanie. , J. Chromatogr. B Anal. Technol. Biomed. Life Sci., Volume 923-924, p.98–101, (2013)
The Use of a Peptidic Scaffold for the Formation of Stable Guanine Tetrads: Control of a H-bonded Pattern in Water., Murat, Pierre, Gennaro Béatrice, Garcia Julian, Spinelli Nicolas, Dumy Pascal, and Defrancq Eric , Chem. - A Eur. J., Volume 17, Number 21, p.5791–5795, S5791/1–S5791/21, (2011)
Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands, Bossaert, Madeleine, Pipier Angélique, Riou Jean-Francois, Noirot Céline, Nguyễn Linh-Trang, Serre Remy-Felix, Bouchez Olivier, Defrancq Eric, Calsou Patrick, Britton Sébastien, et al. , eLife, 06/2021, Volume 10, p.e65184, (2021)
Towards the Development of Photo-Reactive Ruthenium(II) Complexes Targeting Telomeric G-Quadruplex DNA., Weynand, Justin, Diman Aurelie, Abraham Michael, Marcelis Lionel, Jamet Hélène, Decottignies Anabelle, Dejeu Jérôme, Defrancq Eric, and Elias Benjamin. , Chem. - A Eur. J., Volume 24, Number 72, p.19216–19227, (2018)
Template-mediated stabilization of a DNA G-quadruplex formed in the HIV-1 promoter and comparative binding studies., Bonnat, Laureen, Bar Laure, Gennaro Béatrice, Bonnet Hugues, Jarjayes Olivier, Thomas Fabrice, Dejeu Jérôme, Defrancq Eric, and Lavergne Thomas , Chem. - A Eur. J., Volume 23, Number 23, p.5602–5613, (2017)
Templated Formation of Discrete RNA and DNA:RNA Hybrid G-Quadruplexes and Their Interactions with Targeting Ligands., Bonnat, Laureen, Dejeu Jérôme, Bonnet Hugues, Gennaro Béatrice, Jarjayes Olivier, Thomas Fabrice, Lavergne Thomas, and Defrancq Eric , Chem. - A Eur. J., Volume 22, Number 9, p.3139–3147, (2016)
Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies., Murat, Pierre, Bonnet Romaric, Van der Heyden Angeline, Spinelli Nicolas, Labbe Pierre, Monchaud David, Teulade-Fichou Marie-Paule, Dumy Pascal, and Defrancq Eric , Chem. - A Eur. J., Volume 16, Number 20, p.6106–6114, S6106/1–S6106/16, (2010)
Targeting G-Rich DNA Structures with Photoreactive Bis-Cyclometallated Iridium(III) Complexes, Weynand, Justin, Bonnet Hugues, Loiseau Frédérique, Ravanat Jean-Luc, Dejeu Jérôme, Defrancq Eric, and Elias Benjamin. , Chemistry – A European Journal, Volume 25, p.12730-12739, (2019)
Synthesis and photophysical studies of a multivalent photoreactive RuII-calix[4]arene complex bearing RGD-containing cyclopentapeptides., Kajouj, Sofia, Marcelis Lionel, Mattiuzzi Alice, Grassin Adrien, Dufour Damien, Van Antwerpen Pierre, Boturyn Didier, Defrancq Eric, Surin Mathieu, De Winter Julien, et al. , Beilstein J. Org. Chem., Volume 14, p.1758–1768, (2018)
Synthesis and characterization of oligonucleotide conjugates bearing electroactive labels., Moreau, Julie, Dendane Nabil, Schollhorn Bernd, Spinelli Nicolas, Fave Claire, and Defrancq Eric , Bioorg. Med. Chem. Lett., Volume 23, Number 4, p.955–958, (2013)
Surface-immobilized DNAzyme-type biocatalysis., Stefan, Loic, Lavergne Thomas, Spinelli Nicolas, Defrancq Eric, and Monchaud David. , Nanoscale, Volume 6, Number 5, p.2693–2701, (2014)
Surface plasmon resonance study of the interaction of N-methyl mesoporphyrin IX with G-quadruplex DNA, Perenon, M, Bonnet Hugues, Lavergne Thomas, Dejeu Jérôme, and Defrancq Eric , Phys. Chem. Chem. Phys., 02/2020, Volume 22, p.4158-4164, (2020)
Surface patterning of (bio)molecules onto the inner wall of fused-silica capillary tubes., Dendane, Nabil, Hoang Antoine, Renaudet Olivier, Vinet Francoise, Dumy Pascal, and Defrancq Eric , Lab Chip, Volume 8, Number 12, p.2161–2163, (2008)
Specificity of light-induced covalent adduct formation between RuII oligonucleotide conjugates and target sequences for gene silencing applications., Marcelis, Lionel, Surin Mathieu, Lartia Remy, Moucheron Cecile, Defrancq Eric, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Volume 2014, Number 19, p.3016–3022, (2014)
Sensor Based on Aptamer Folding to Detect Low-Molecular Weight Analytes., Osypova, Alina, Thakar Dhruv, Dejeu Jérôme, Bonnet Hugues, Van der Heyden Angeline, Dubacheva Galina V., Richter Ralf P., Defrancq Eric, Spinelli Nicolas, Guerente Liliane, et al. , Anal. Chem. (Washington, DC, United States), Volume 87, Number 15, p.7566–7574, (2015)
Scaffold stabilization of a G-triplex and study of its interactions with G-quadruplex targeting ligands, Bonnat, Laureen, Dautriche Maelle, Saidi Taous, Revol-Cavalier Johana, Dejeu Jérôme, Defrancq Eric, and Lavergne Thomas , Org. Biomol. Chem., Volume 17, p.8726-8736, (2019)
Scaffold stabilization of a G-triplex and study of its interactions with G-quadruplex targeting ligands., Bonnat, Laureen, Dautriche Maelle, Saidi Taous, Revol-Cavalier Johana, Dejeu Jérôme, Defrancq Eric, and Lavergne Thomas , Org. Biomol. Chem., Volume 17, p.8726–8736, (2019)
Ruthenium oligonucleotides, targeting HPV16 E6 oncogene, inhibit the growth of cervical cancer cells under illumination by a mechanism involving p53., Reschner, A, Bontems S, Le Gac Stephane, Lambermont J, Marcelis L, Defrancq Eric, Hubert P, Moucheron C, A De Mesmaeker Kirsch-, Raes M, et al. , Gene Ther., Volume 20, Number 4, p.435–443, (2013)
A Rigid Dinuclear Ruthenium(II) Complex as an Efficient Photoactive Agent for Bridging Two Guanine Bases of a Duplex or Quadruplex Oligonucleotide., Rickling, Stephane, Ghisdavu Liana, Pierard Frederic, Gerbaux Pascal, Surin Mathieu, Murat Pierre, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Chem. - A Eur. J., Volume 16, Number 13, p.3951–3961, S3951/1–S3951/9, (2010)
Redox-Active Bis-Cyclometalated Iridium(III) Complex as a DNA Photo-Cleaving Agent, Weynand, Justin, Moreno-Betancourt Angélica, Loiseau Frédérique, Berthet Nathalie, Defrancq Eric, and Elias Benjamin , Inorganic Chemistry, 01/2020, Volume 59, p.2426-2433, (2020)
Recent progress in the design of G-quadruplex based electrochemical aptasensors, Dejeu, Jérôme, Van der Heyden A., Spinelli N., Defrancq Eric, and Coche-Guérente L. , Current Opinion in Electrochemistry, 07/2021, p.100812, (2021)
Recent developments in oligonucleotide conjugation., Singh, Yashveer, Murat Pierre, and Defrancq Eric , Chem. Soc. Rev., Volume 39, Number 6, p.2054–2070, (2010)
RAFT Nano-constructs: surfing to biological applications., Boturyn, Didier, Defrancq Eric, Dolphin Gunnar T., Garcia Julian, Labbe Pierre, Renaudet Olivier, and Dumy Pascal , J. Pept. Sci., Volume 14, Number 2, p.224–240, (2008)
Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties., Flack, Theodore, Constantin Thibaut, Penasse Sylvain, Dejeu Jérôme, Gennaro Béatrice, Jourdan Muriel, Laguerre Aurelien, Pirrotta Marc, Monchaud David, Spinelli Nicolas, et al. , Chem. - A Eur. J., Volume 22, Number 5, p.1760–1767, (2016)
Post-synthetic transamination at position N4 of cytosine in oligonucleotides assembled with routinely used phosphoramidites, Lartia, Remy, Vallée Coelio, and Defrancq Eric , Org. Biomol. Chem., Volume 18, p.9632-9638, (2020)
Post-synthetic transamination at position N4 of cytosine in oligonucleotides assembled with routinely used phosphoramidites, Lartia, Remy, Vallée Coelio, and Defrancq Eric , Org. Biomol. Chem., 11/2020, p.-, (2020)
Plasmon-induced CD response of oligonucleotide-conjugated metal nanoparticles., Gerard, Valerie A., Gun'ko Yurii K., Defrancq Eric, and Govorov Alexander O. , Chem. Commun. (Cambridge, United Kingdom), Volume 47, Number 26, p.7383–7385, (2011)
The pKa value of the proximal water molecule trans to a high-valent MnV=O porphyrin: towards the control of reactivity by pH., Saint-Germes, Laurie, Bar Laure, Dejeu Jérôme, Spinelli Nicolas, Defrancq Eric, and Pratviel Genevieve. , Dalt. Trans., Volume 46, Number 36, p.12088–12094, (2017)
A photoreactive ruthenium(II) complex tethered to a guanine-containing oligonucleotide: A biomolecular tool that behaves as a "Seppuku Molecule"., Le Gac, Stephane, Rickling Stephane, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Angew. Chemie, Int. Ed., Volume 48, Number 6, p.1122–1125, (2009)
Photo-reactive RuII-oligonucleotide conjugates: influence of an intercalating ligand on the inter- and intra-strand photo-ligation processes., Le Gac, Stephane, Foucart Martin, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Dalt. Trans., Volume 39, Number 40, p.9672–9683, (2010)
Photoinduced Electron Transfer from Tryptophan to RuIITAP Complexes: The Primary Process for Photo-Cross-Linking with Oligopeptides., Rebarz, Mateusz, Ghesquiere Jonathan, Boisdenghien Arnaud, Defrancq Eric, Moucheron Cecile, and De Mesmaeker Andree. Kirsch- , Inorg. Chem., Volume 49, Number 23, p.10867–10874, (2010)
Photodetection of DNA mismatches by dissymmetric Ru(ii) acridine based complexes, Gillard, Martin, Laramee-Milette Baptiste, Deraedt Quentin, Hanan Garry S., Loiseau Frédérique, Dejeu Jérôme, Defrancq Eric, Elias Benjamin., and Marcelis Lionel , Inorg. Chem. Front., p.2260-2270, (2019)
Photo-Cross-Linking between Polymers Derivatized with Photoreactive Ruthenium-1,4,5,8-Tetraazaphenanthrene Complexes and Guanine-Containing Oligonucleotides., Deroo, Stephanie, Toncheva Veska, Defrancq Eric, Moucheron Cecile, Schacht Etienne, and De Mesmaeker Andree. Kirsch- , Biomacromolecules, Volume 8, Number 11, p.3503–3510, (2007)
Photocrosslinking between Peptide-Peptide or Peptide-Oligonucleotide by RuII-TAP Complexes., Ghesquiere, Jonathan, Gauthier Nicolas, De Winter Julien, Gerbaux Pascal, Moucheron Cecile, Defrancq Eric, and De Mesmaeker Andree. Kirsch- , Chem. - A Eur. J., Volume 18, Number 1, p.55–364, S355/1–S355/7, (2012)
Phosphorylating Reagent-Free Synthesis of 5'-Phosphate Oligonucleotides by Controlled Oxidative Degradation of Their 5'-End., Sallamand, Corinne, Miscioscia Audrey, Lartia Remy, and Defrancq Eric , Org. Lett., Volume 14, Number 8, p.2030–2033, (2012)
Parameters influencing the photo-induced electron transfer from tryptophan-containing peptides to a RuII complex: a systematic study., Garnir, Kevin, Estalayo-Adrian Sandra, Lartia Remy, De Winter Julien, Defrancq Eric, Surin Mathieu, Lemaur Vincent, Gerbaux Pascal, and Moucheron Cecile. , Faraday Discuss., Volume 185, p.267–284, (2015)
Palladium-Mediated Labeling of Nucleic Acids., Defrancq, Eric, and Messaoudi Samir. , ChemBioChem, Volume 18, Number 5, p.426–431, (2017)
An oxime-based glycocluster microarray., Hoang, Antoine, Laigre Eugenie, Goyard David, Defrancq Eric, Vinet Francoise, Dumy Pascal, and Renaudet Olivier , Org. Biomol. Chem., Volume 15, Number 24, p.5135–5139, (2017)
Oxidizing Ru(II) Complexes as Irreversible and Specific Photocrosslinking Agents of Oligonucleotide Duplexes., Ghizdavu, Liana, Pierard Frederic, Rickling Stephane, Aury Sabrina, Surin Mathieu, Beljonne David, Lazzaroni Roberto, Murat Pierre, Defrancq Eric, Moucheron Cecile, et al. , Inorg. Chem., Volume 48, Number 23, p.10988–10994, (2009)
Optical properties and in vitro biological studies of oligonucleotide-modified quantum dots., Gerard, Valerie A., Freeley Mark, Defrancq Eric, Fedorov Anatoly V., and Gun'ko Yurii K. , J. Nanomater., p.463951, 11 pp., (2013)
Oligonucleotide Sequential Bis-Conjugation via Click-Oxime and Click-Huisgen Procedures., Meyer, Albert, Spinelli Nicolas, Dumy Pascal, Vasseur Jean-Jacques, Morvan Francois, and Defrancq Eric , J. Org. Chem., Volume 75, Number 11, p.3927–3930, (2010)
Oligonucleotide Functionalization of Hollow Triangular Gold Silver Alloy Nanoboxes., Keegan, Gemma L., Aherne Damian, Defrancq Eric, Gun'ko Yurii K., and Kelly John M. , J. Phys. Chem. C, Volume 117, Number 1, p.669–676, (2013)
Oligonucleotide duplexes with tethered photoreactive ruthenium(II) complexes: influence of the ligands and their linker on the photoinduced electron transfer and crosslinking processes of the two strands., Deroo, Stephanie, Le Gac Stephane, Ghosh Sumana, Villien Mathilde, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, Dumy Pascal, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Number 4, p.524–532, (2009)
A novel conformationally constrained parallel G quadruplex., Murat, Pierre, Cressend Delphine, Spinelli Nicolas, Van der Heyden Angeline, Labbe Pierre, Dumy Pascal, and Defrancq Eric , ChemBioChem, Volume 9, Number 16, p.2588–2591, (2008)
The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells., Sabater, Laurent, Nicolau-Travers Marie-Laure, De Rache Aurore, Prado Enora, Dejeu Jérôme, Bombarde Oriane, Lacroix Joris, Calsou Patrick, Defrancq Eric, Mergny Jean-Louis, et al. , JBIC, J. Biol. Inorg. Chem., Volume 20, Number 4, p.729–738, (2015)
New Solid Support for the Synthesis of 3'-Oligonucleotide Conjugates through Glyoxylic Oxime Bond Formation., Spinelli, Nicolas, Edupuganti Om Prakash, Defrancq Eric, and Dumy Pascal , Org. Lett., Volume 9, Number 2, p.219–222, (2007)
New Ruthenium-Based Probes for Selective G-Quadruplex Targeting., Piraux, Guillaume, Bar Laure, Abraham Michael, Lavergne Thomas, Jamet Hélène, Dejeu Jérôme, Marcelis Lionel, Defrancq Eric, and Elias Benjamin. , Chem. - A Eur. J., Volume 23, Number 49, p.11872–11880, (2017)
Negative SPR Signals during Low Molecular Weight Analyte Recognition, Bonnet, Hugues, Coche-Guérente L., Defrancq Eric, Spinelli N., Van der Heyden Angeline, and Dejeu Jérôme , Analytical Chemistry, 02/2021, Volume 93, Issue 8, p.4134–4140, (2021)

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