78 resultats trouvés
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Multimeric RGD-Based Strategies for Selective Drug Delivery to Tumor Tissues,
, Pharmaceutics, 02/2023, Volume 15, (2023)
2-Hydroxy-4-methoxybenzyl as a Thiol-Protecting Group for Directed-Disulfide Bond Formation,
, Organic Letters, 05/2022, Volume 24, Issue 18, p.3407–3410, (2022)
Chemical Synthesis of a Functional Fluorescent-Tagged α-Bungarotoxin,
, Toxins, 01/2022, Volume 14, p.79, (2022)
MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries,
, Biomedicine & Pharmacotherapy, Volume 150, p.113094, (2022)
Multiplexed Imaging Reveals the Spatial Relationship of the Extracellular Acidity-Targeting pHLIP with Necrosis, Hypoxia, and the Integrin-Targeting cRGD Peptide,
, Cells, 11/2022, Volume 11, (2022)
Multivalent glycocyclopeptides: conjugation methods and biological applications,
, Chem. Soc. Rev., 10/2022, Volume 51, p.8756 – 8783, (2022)
Determination of the Rituximab Binding Site to the CD20 Epitope Using SPOT Synthesis and Surface Plasmon Resonance Analyses,
, Analytical Chemistry, 04/2021, Volume 93, Issue 17, p.6865−6872, (2021)
Impact of multimeric ferrocene-containing cyclodecapeptide scaffold on host-guest interactions at a β-cyclodextrin covered surface.,
, ChemPhysChem, 08/2021, Volume 22, p.2231–2239, (2021)
Les vecteurs peptidiques, GPS du principe actif,
, Actualité Chimique, 12/2121, Volume 468, p.21-22, (2021)
Ratiometric Luminescence Detection of Copper(I) by a Resonant System Comprising Two Antenna/Lanthanide Pairs,
, Inorganic Chemistry, 11/2021, Volume 60, p.17426−17434, (2021)
Antimicrobial Peptides as Probes in Biosensors Detecting Whole Bacteria: A Review,
, Molecules, 04/2020, Volume 25, (2020)
Heparan sulfate co-immobilized with cRGD ligands and BMP2 on biomimetic platforms promotes BMP2-mediated osteogenic differentiation,
, Acta Biomaterialia, 07/2020, Volume 114, p.90 - 103, (2020)
Impact of Antigen Density on Recognition by Monoclonal Antibodies,
, Analytical Chemistry, 03/2020, Volume 92, p.5396−5403, (2020)
Multimeric Presentation of RGD Peptidomimetics Enhances Integrin Binding and Tumor Cell Uptake,
, Chemistry – A European Journal, 03/2020, Volume 26, p.7492 – 7496, (2020)
Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer,
, Clinical Cancer Research, 09/2020, Volume 26, Issue 23, p.6230-6241, (2020)
Synthesis and Biological Characterization of Monomeric and Tetrameric RGD-Cryptophycin Conjugates,
, Chemistry – A European Journal, 01/2020, Volume 26, p.2602 – 2605, (2020)
Using Native Chemical Ligation for Site-specific Synthesis of Hetero-bis-lanthanide Peptide Conjugates: Application to Ratiometric Visible or Near-infrared Detection of Zn2+,
, Chemistry – A European Journal, 07/2020, Volume 26, p.13476-13483, (2020)
Antimicrobial peptide arrays for wide spectrum sensing of pathogenic bacteria,
, Talanta, Volume 203, p.322–327, (2019)
Influence of the Spatial Conformation of Charged Ligands on the Optical Properties of Gold Nanoclusters,
, The Journal of Physical Chemistry C, Volume 123, p.26705-26717, (2019)
Influence of the Spatial Conformation of Charged Ligands on the Optical Properties of Gold Nanoclusters.,
, J. Phys. Chem. C, Volume 123, p.26705–26717, (2019)
Multifunctional Glycoconjugates for Recruiting Natural Antibodies against Cancer Cells.,
, Chem. - Eur. J., Volume 25, p.15508–15515, (2019)
Multifunctional Glycoconjugates for Recruiting Natural Antibodies against Cancer Cells,
, Chemistry – A European Journal, Volume 25, p.15508-15515, (2019)
Synthesis by native chemical ligation and characterization of the scorpion toxin AmmTx3,
, Bioorganic & Medicinal Chemistry, Volume 27, p.247 - 253, (2019)
Design of RGD-ATWLPPR peptide conjugates for the dual targeting of $\alpha$V$\beta$3 integrin and neuropilin-1.,
, Org. Biomol. Chem., Volume 16, Number 22, p.4101–4107, (2018)
Mercury trithiolate binding (HgS3) to a de novo designed cyclic decapeptide with three preoriented cysteine side chains.,
, Inorg. Chem., Volume 57, Number 5, p.2705–2713, (2018)
Positron emission tomography of cerebral angiogenesis and TSPO expression in a mouse model of chronic hypoxia.,
, J. Cereb. Blood Flow Metab., Volume 38, Number 4, p.687–696, (2018)
Synthesis and photophysical studies of a multivalent photoreactive RuII-calix[4]arene complex bearing RGD-containing cyclopentapeptides.,
, Beilstein J. Org. Chem., Volume 14, p.1758–1768, (2018)
Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model.,
, EJNMMI Res., Volume 8, Number 1, p.1–10, (2018)
67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice.,
, Nucl. Med. Commun., Volume 38, Number 4, p.347–355, (2017)
Binding of the chemokine CXCL12α to its natural extracellular matrix ligand heparan sulfate enables myoblast adhesion and facilitates cell motility.,
, Biomaterials, Volume 123, p.24–38, (2017)
Development of a selective cell capture and release assay: impact of clustered RGD ligands.,
, J. Mater. Chem. B Mater. Biol. Med., Volume 5, Number 24, p.4745–4753, (2017)
Luminescent Zinc Fingers: Zn-Responsive Neodymium Near-Infrared Emission in Water.,
, Chem. - A Eur. J., Volume 23, Number 46, p.10992–10996, (2017)
"Polymultivalent" Polymer-Peptide Cluster Conjugates for an Enhanced Targeting of Cells Expressing $\alpha$v$\beta$3 Integrins.,
, Bioconjug. Chem., Volume 28, Number 9, p.2241–2245, (2017)
Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model.,
, Mol. Ther., Volume 25, Number 2, p.534–546, (2017)
$\alpha$V$\beta$3 Integrin-Targeted Radionuclide Therapy with 64Cu-cyclam-RAFT-c(-RGDfK-)4.,
, Mol. Cancer Ther., Volume 15, Number 9, p.2076–2085, (2016)
From Peptide Aptamers to Inhibitors of FUR, Bacterial Transcriptional Regulator of Iron Homeostasis and Virulence.,
, ACS Chem. Biol., Volume 11, Number 9, p.2519–2528, (2016)
Influence of Pre-organised Architecture on Cell Adhesion by Using Multivalent RGD Compounds.,
, ChemBioChem, Volume 17, Number 6, p.515–520, (2016)
Biomolecular Assemblies Combining Two Orthogonal Copper-Mediated Ligations in a One-Pot Reaction.,
, Chem. - A Eur. J., Volume 21, Number 16, p.6022–6026, (2015)
Controlled surface density of RGD ligands for cell adhesion: evidence for ligand specificity by using QCM-D.,
, J. Mater. Chem. B Mater. Biol. Med., Volume 3, Number 27, p.5577–5587, (2015)
Multivalency: influence of the residence time and the retraction rate on rupture forces measured by AFM.,
, J. Mater. Chem. B Mater. Biol. Med., Volume 3, Number 9, p.1801–1812, (2015)
Targeted radionuclide therapy with RAFT-RGD radiolabelled with 90Y or 177Lu in a mouse model of $\alpha$v$\beta$3-expressing tumours.,
, Eur. J. Nucl. Med. Mol. Imaging, Volume 42, Number 2, p.252–263, (2015)
Co-liposomes comprising a lipidated multivalent RGD-peptide and a cationic gemini cholesterol induce selective gene transfection in $\alpha$v$\beta$3 and $\alpha$v$\beta$5 integrin receptor-rich cancer cells.,
, J. Mater. Chem. B Mater. Biol. Med., Volume 2, Number 35, p.5758–5767, (2014)
Oxime Ligation: A Chemoselective Click-Type Reaction for Accessing Multifunctional Biomolecular Constructs.,
, Chem. - A Eur. J., Volume 20, Number 1, p.34–41, (2014)
PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of 64Cu-cyclam-RAFT-c(-RGDfK-)4in vivo.,
, Eur. J. Pharm. Biopharm., Volume 86, Number 3, p.478–486, (2014)
Redox-driven host-guest interactions allow the controlled release of captured cells on RGD-functionalized surfaces.,
, ChemBioChem, Volume 15, Number 3, p.377–381, (2014)
Engineering of biomolecules for sensing and imaging applications.,
, J. Drug Deliv. Sci. Technol., Volume 23, Number 1, p.5–15, (2013)
In vivo molecular imaging of atherosclerotic lesions in ApoE-/- mice using VCAM-1-specific, 99Tc-labeled peptidic sequences.,
, J. Nucl. Med., Volume 54, Number 8, p.1442–1449, (2013)
Integrin and matrix metalloprotease dual-targeting with an MMP substrate-RGD conjugate.,
, Org. Biomol. Chem., Volume 11, Number 3, p.448–452, (2013)
Micro-positron emission tomography/contrast-enhanced computed tomography imaging of orthotopic pancreatic tumor-bearing mice using the $\alpha$v$\beta$3 integrin tracer 64Cu-labeled cyclam-RAFT-c(-RGDfK-)4.,
, Mol. Imaging, Volume 12, Number 6, p.376–387, (2013)
Near-infrared optical guided surgery of highly infiltrative fibrosarcomas in cats using an anti-$\alpha$vss3 integrin molecular probe.,
, Cancer Lett. (New York, NY, United States), Volume 334, Number 2, p.188–195, (2013)
Fluorescent molecules for surgery.,
, Actual. Chim., Volume 366, p.23–28, (2012)
Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe 64Cu-cyclam-RAFT-c(-RGDfK-)4.,
, Angiogenesis, Volume 15, Number 4, p.569–580, (2012)
Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin $\alpha$v$\beta$3 targeting using single photon emission computed tomography and optical imaging.,
, Cancer Sci., Volume 103, Number 6, p.1105–1110, (2012)
Access to Biomolecular Assemblies through One-Pot Triple Orthogonal Chemoselective Ligations.,
, Angew. Chemie, Int. Ed., Volume 50, Number 8, p.1901–1904, S1901/1–S1901/32, (2011)
Noninvasive visualization and quantification of tumor $\alpha$V$\beta$3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4.,
, Nucl. Med. Biol., Volume 38, Number 4, p.529–540, (2011)
Redox strategy for reversible attachment of biomolecules using bifunctional linkers.,
, Chem. Commun. (Cambridge, United Kingdom), Volume 47, Number 12, p.3565–3567, (2011)
Targeted delivery of a proapoptotic peptide to tumors in vivo.,
, J. Drug Target., Volume 19, Number 7, p.582–588, (2011)
Application of click-click chemistry to the synthesis of new multivalent RGD conjugates.,
, Org. Biomol. Chem., Volume 8, Number 22, p.5133–5138, (2010)
Cell adhesion through clustered ligand on fluid supported lipid bilayers.,
, Org. Biomol. Chem., Volume 8, Number 7, p.1531–1534, (2010)
Molecular engineering of biomolecules for nanobio-sciences.,
, Int. J. Nanotechnol., Volume 7, Number 4/5/6/7/8, p.738–752, (2010)
RGD-cyclam conjugate: Synthesis and potential application for positron emission tomography.,
, Bioorg. Med. Chem. Lett., Volume 20, Number 18, p.5422–5425, (2010)
Biomolecular assembly by iterative oxime ligations.,
, Bioorg. Med. Chem. Lett., Volume 19, Number 14, p.3880–3883, (2009)
Clustering and Internalization of Integrin $\alpha$v$\beta$3 With a Tetrameric RGD-synthetic Peptide.,
, Mol. Ther., Volume 17, Number 5, p.837–843, (2009)
Drug development in oncology assisted by noninvasive optical imaging.,
, Int. J. Pharm., Volume 379, Number 2, p.309–316, (2009)
A Gadolinium-Binding Cyclodecapeptide with a Large High-Field Relaxivity Involving Second-Sphere Water.,
, Chem. - A Eur. J., Volume 15, Number 29, p.7083–7093, S7083/1–S7083/8, (2009)
Highly efficient cell adhesion on beads functionalized with clustered peptide ligands.,
, Org. Biomol. Chem., Volume 7, Number 20, p.4159–4162, (2009)
One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations.,
, Angew. Chemie, Int. Ed., Volume 48, Number 14, p.2576–2579, (2009)
Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells.,
, Org. Biomol. Chem., Volume 7, Number 2, p.221–224, (2009)
1-Ethoxyethylidene, a New Group for the Stepwise SPPS of Aminooxyacetic Acid Containing Peptides.,
, J. Org. Chem., Volume 73, Number 3, p.983–991, (2008)
Chemical and Biological Evaluations of an 111In-Labeled RGD-Peptide Targeting Integrin Alpha(V) Beta(3) in a Preclinical Tumor Model.,
, Cancer Biother. Radiopharm., Volume 23, Number 6, p.691–700, (2008)
RAFT Nano-constructs: surfing to biological applications.,
, J. Pept. Sci., Volume 14, Number 2, p.224–240, (2008)
Synthesis and biological characterization of targeted pro-apoptotic peptide.,
, ChemBioChem, Volume 9, Number 14, p.2326–2332, (2008)
Activatable probes for non-invasive small animal fluorescence imaging.,
, Nucl. Instruments Methods Phys. Res. Sect. A Accel. Spectrometers, Detect. Assoc. Equip., Volume 571, Number 1+2, p.165–168, (2007)
In vivo noninvasive optical imaging of receptor-mediated RGD internalization using self-quenched Cy5-labeled RAFT-c(-RGDfK-)4.,
, Mol. Imaging, Volume 6, Number 1, p.43–55, (2007)
Cyclodecapeptides to mimic the radical site of tyrosyl-containing proteins.,
, J. Pept. Sci., Volume 12, Number 9, p.612–619, (2006)
Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template.,
, Langmuir, Volume 22, Number 19, p.8134–8143, (2006)