Département de chimie moléculaire

X-Ray Structure of the Key Synthetic Intermediate of a Cancer-Related Sialyl-Tn Antigen Analogue., Renaudet, Olivier, Philouze Christian, Bailly Corinne, Durif Andre, and Dumy Pascal , J. Chem. Crystallogr., Volume 41, Number 2, p.204–208, (2011)

Versatile Introduction of Azido Moiety into Oligonucleotides through Diazo Transfer Reaction., Lartia, Remy, Murat Pierre, Dumy Pascal, and Defrancq Eric , Org. Lett., Volume 13, Number 20, p.5672–5675, (2011)

The Use of a Peptidic Scaffold for the Formation of Stable Guanine Tetrads: Control of a H-bonded Pattern in Water., Murat, Pierre, Gennaro Béatrice, Garcia Julian, Spinelli Nicolas, Dumy Pascal, and Defrancq Eric , Chem. - A Eur. J., Volume 17, Number 21, p.5791–5795, S5791/1–S5791/21, (2011)

Unlimited growth of host-guest multilayer films based on functionalized neutral polymers., Dubacheva, Galina V., Dumy Pascal, Auzely Rachel, Schaaf Pierre, Boulmedais Fouzia, Jierry Loic, Guerente Liliane, and Labbe Pierre , Soft Matter, Volume 6, Number 16, p.3747–3750, (2010)

Uniform intratumoral distribution of radioactivity produced using two different radioagents, 64Cu-cyclam-RAFT-c(-RGDfK-)4 and 64Cu-ATSM, improves therapeutic efficacy in a small animal tumor model., Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Sugyo Aya, Yoshii Yukie, Nagatsu Kotaro, Zhang Ming-Rong, Fujibayashi Yasuhisa, Dumy Pascal, Boturyn Didier, et al. , EJNMMI Res., Volume 8, Number 1, p.1–10, (2018)

Thiyl Glycosylation of Propargylated Octasilsesquioxane: Synthesis and Lectin-Binding Properties of Densely Glycosylated Clusters on a Cubic Platform., Marra, Alberto, Staderini Samuele, Berthet Nathalie, Dumy Pascal, Renaudet Olivier, and Dondoni Alessandro. , European J. Org. Chem., Volume 2013, Number 6, p.1144–1149, (2013)

Thiol-ene and thiol-yne-based synthesis of glycodendrimers as nanomolar inhibitors of wheat germ agglutinin., Ghirardello, Mattia, Oeberg Kim, Staderini Samuele, Renaudet Olivier, Berthet Nathalie, Dumy Pascal, Hed Yvonne, Marra Alberto, Malkoch Michael, and Dondoni Alessandro. , J. Polym. Sci. Part A Polym. Chem., Volume 52, Number 17, p.2422–2433, (2014)

Tetravalent glycocyclopeptide with nanomolar affinity to wheat germ agglutinin., Fiore, Michele, Berthet Nathalie, Marra Alberto, Gillon Emilie, Dumy Pascal, Dondoni Alessandro, Imberty Anne, and Renaudet Olivier , Org. Biomol. Chem., Volume 11, Number 41, p.7113–7122, (2013)

Tethered Bilayer Lipid Membranes on Mixed Self-Assembled Monolayers of a Novel Anchoring Thiol: Impact of the Anchoring Thiol Density on Bilayer Formation., Basit, Hajra, Van der Heyden Angeline, Gondran Chantal, Nysten Bernard, Dumy Pascal, and Labbe Pierre , Langmuir, Volume 27, Number 23, p.14317–14328, (2011)

Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies., Murat, Pierre, Bonnet Romaric, Van der Heyden Angeline, Spinelli Nicolas, Labbe Pierre, Monchaud David, Teulade-Fichou Marie-Paule, Dumy Pascal, and Defrancq Eric , Chem. - A Eur. J., Volume 16, Number 20, p.6106–6114, S6106/1–S6106/16, (2010)

Targeted delivery of activatable fluorescent pro-apoptotic peptide into live cells., Foillard, Stephanie, Sancey Lucie, Coll Jean-Luc, Boturyn Didier, and Dumy Pascal , Org. Biomol. Chem., Volume 7, Number 2, p.221–224, (2009)

Targeted delivery of a proapoptotic peptide to tumors in vivo., Dufort, Sandrine, Sancey Lucie, Hurbin Amandine, Foillard Steephanie, Boturyn Didier, Dumy Pascal, and Coll Jean-Luc. , J. Drug Target., Volume 19, Number 7, p.582–588, (2011)

Systemic Delivery of Tumor-Targeted Bax-Derived Membrane-Active Peptides for the Treatment of Melanoma Tumors in a Humanized SCID Mouse Model., Karageorgis, Anastassia, Claron Michael, Juge Romain, Aspord Caroline, Thoreau Fabien, Leloup Claire, Kucharczak Jerome, Plumas Joel, Henry Maxime, Hurbin Amandine, et al. , Mol. Ther., Volume 25, Number 2, p.534–546, (2017)

Synthesis of N-acridinyl-N'-alkylguanidines: Dramatic influence of amine to guanidine replacement on the physicochemical properties., Zeghida, Walid, Debray Julien, Michel Carine, Milet Anne, Dumy Pascal, and Demeunynck Martine , Bioorg. Med. Chem. Lett., Volume 18, Number 17, p.4779–4782, (2008)

Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells [Retraction of document cited in CA152:592290]., Renaudet, Olivier, Krenek Karel, Bossu Isabelle, Dumy Pascal, Kadek Alan, Adamek David, Vanek Ondrej, Kavan Daniel, Gazak Radek, Sulc Miroslav, et al. , J. Am. Chem. Soc., Volume 136, Number 3, p.1156, (2014)

Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells., Renaudet, Olivier, Krenek Karel, Bossu Isabelle, Dumy Pascal, Kadek Alan, Adamek David, Vanek Ondrej, Kavan Daniel, Gazak Radek, Sulc Miroslav, et al. , J. Am. Chem. Soc., Volume 132, Number 19, p.6800–6808, (2010)

Synthesis of multi-antigenic platforms as vaccine candidates against cancers., Fiore, Michele, Thomas Baptiste, Dulery Vincent, Dumy Pascal, and Renaudet Olivier , New J. Chem., Volume 37, Number 2, p.286–289, (2013)

Synthesis of heteroglycoclusters by using orthogonal chemoselective ligations., Thomas, Baptiste, Fiore Michele, Bossu Isabelle, Dumy Pascal, and Renaudet Olivier , Beilstein J. Org. Chem., Volume 8, p.421–427, No. 47, (2012)

Synthesis of Glycocyclopeptides by Click Chemistry and Inhibition Assays with Lectins., Bossu, Isabelle, Berthet Nathalie, Dumy Pascal, and Renaudet Olivier , J. Carbohydr. Chem., Volume 30, Number 7-9, p.458–468, (2011)

Synthesis and evaluation of fused bispyrimidinoacridines as novel pentacyclic analogues of quadruplex-binder BRACO-19., Debray, Julien, Zeghida Walid, Jourdan Muriel, Monchaud David, Dheu-Andries Marie-Louise, Dumy Pascal, Teulade-Fichou Marie-Paule, and Demeunynck Martine , Org. Biomol. Chem., Volume 7, Number 24, p.5219–5228, (2009)

Synthesis and Biological Evaluation of Clicked Curcumin and Clicked KLVFFA Conjugates as Inhibitors of $\beta$-Amyloid Fibril Formation., Ouberai, Myriam, Dumy Pascal, Chierici Sabine, and Garcia Julian. , Bioconjug. Chem., Volume 20, Number 11, p.2123–2132, (2009)

Synthesis and biological characterization of targeted pro-apoptotic peptide., Foillard, Stephanie, Jin Zhao-hui, Garanger Elisabeth, Boturyn Didier, Favrot Marie-Christine, Coll Jean-Luc, and Dumy Pascal , ChemBioChem, Volume 9, Number 14, p.2326–2332, (2008)

Surface patterning of (bio)molecules onto the inner wall of fused-silica capillary tubes., Dendane, Nabil, Hoang Antoine, Renaudet Olivier, Vinet Francoise, Dumy Pascal, and Defrancq Eric , Lab Chip, Volume 8, Number 12, p.2161–2163, (2008)

Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction., Laudet, Beatrice, Barette Caroline, Dulery Vincent, Renaudet Olivier, Dumy Pascal, Metz Alexandra, Prudent Renaud, Deshiere Alexandre, Dideberg Otto, Filhol Odile, et al. , Biochem. J., Volume 408, Number 3, p.363–373, (2007)

RGD-cyclam conjugate: Synthesis and potential application for positron emission tomography., Galibert, Mathieu, Jin Zhao-hui, Furukawa Takako, Fukumura Toshimitsu, Saga Tsuneo, Fujibayashi Yasuhisa, Dumy Pascal, and Boturyn Didier , Bioorg. Med. Chem. Lett., Volume 20, Number 18, p.5422–5425, (2010)

Re-evaluation of binding properties of recombinant lymphocyte receptors NKR-P1A and CD69 to chemically synthesized glycans and peptides., Rozbesky, Daniel, Krejzova Jana, Krenek Karel, Prchal Jan, Hrabal Richard, Kozisek Milan, Weignerova Lenka, Fiore Michele, Dumy Pascal, Renaudet Olivier, et al. , Int. J. Mol. Sci., Volume 15, Number 1, p.1271–1283, 13 pp., (2014)

Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin $\alpha$v$\beta$3 targeting using single photon emission computed tomography and optical imaging., Briat, Arnaud, Wenk Christiane H. F., Ahmadi Mitra, Claron Michael, Boturyn Didier, Josserand Veronique, Dumy Pascal, Fagret Daniel, Coll Jean-Luc, Ghezzi Catherine, et al. , Cancer Sci., Volume 103, Number 6, p.1105–1110, (2012)

Redox-driven host-guest interactions allow the controlled release of captured cells on RGD-functionalized surfaces., Thakar, Dhruv, Guerente Liliane, Claron Michael, Wenk Christiane H. F., Dejeu Jérôme, Dumy Pascal, Labbe Pierre, and Boturyn Didier , ChemBioChem, Volume 15, Number 3, p.377–381, (2014)

Redox-Active Biomolecular Architectures and Self-Assembled Monolayers Based on a Cyclodecapeptide Regioselectively Addressable Functional Template., Devillers, Charles H., Boturyn Didier, Bucher Christophe, Dumy Pascal, Labbe Pierre, Moutet Jean-Claude, Royal Guy, and Saint-Aman Eric , Langmuir, Volume 22, Number 19, p.8134–8143, (2006)

Redox strategy for reversible attachment of biomolecules using bifunctional linkers., Dubacheva, Galina V., Galibert Mathieu, Guerente Liliane, Dumy Pascal, Boturyn Didier, and Labbe Pierre , Chem. Commun. (Cambridge, United Kingdom), Volume 47, Number 12, p.3565–3567, (2011)

Reactivity of Pyrido[4,3,2-kl]acridines: Regioselective Formation of 6-Substituted Derivatives., Bouffier, Laurent, Demeunynck Martine, Milet Anne, and Dumy Pascal , J. Org. Chem., Volume 69, Number 23, p.8144–8147, (2004)

Randomized Combinatorial Library of Hetero-glyco-clusters (hGC)., Dulery, Vincent, Renaudet Olivier, Wilczewski Marie, Van der Heyden Angeline, Labbe Pierre, and Dumy Pascal , J. Comb. Chem., Volume 10, Number 3, p.368–371, (2008)

RAFT Nano-constructs: surfing to biological applications., Boturyn, Didier, Defrancq Eric, Dolphin Gunnar T., Garcia Julian, Labbe Pierre, Renaudet Olivier, and Dumy Pascal , J. Pept. Sci., Volume 14, Number 2, p.224–240, (2008)

Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer, Jin, Zhao-hui, Tsuji Atsushi B., Degardin Melissa, Sugyo Aya, Obara Satoshi, Wakizaka Hidekatsu, Nagatsu Kotaro, Hu Kuan, Zhang Ming-Rong, Dumy Pascal, et al. , Clinical Cancer Research, 09/2020, Volume 26, Issue 23, p.6230-6241, (2020)

Promotion of sugar-lectin recognition through the multiple sugar presentation offered by regioselectively addressable functionalized templates (RAFT): a QCM-D and SPR study., Wilczewski, Marie, Van der Heyden Angeline, Renaudet Olivier, Dumy Pascal, Guerente Liliane, and Labbe Pierre , Org. Biomol. Chem., Volume 6, Number 6, p.1114–1122, (2008)

Positron emission tomography of cerebral angiogenesis and TSPO expression in a mouse model of chronic hypoxia., Kanno, Iwao, Seki Chie, Takuwa Hiroyuki, Jin Zhao-hui, Boturyn Didier, Dumy Pascal, Furukawa Takako, Saga Tsuneo, Ito Hiroshi, and Masamoto Kazuto. , J. Cereb. Blood Flow Metab., Volume 38, Number 4, p.687–696, (2018)

Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Claron Michael, Boturyn Didier, Coll Jean-Luc, Fukumura Toshimitsu, Fujibayashi Yasuhisa, Dumy Pascal, and Saga Tsuneo. , Angiogenesis, Volume 15, Number 4, p.569–580, (2012)

Phenolic oxime oligomers inhibit Alzheimer's amyloid fibril formation and disaggregate fibrils in vitro., Dolphin, Gunnar T., Renaudet Olivier, Ouberai Myriam, Dumy Pascal, Garcia Julian, and Reymond Jean-Louis. , ChemBioChem, Volume 10, Number 8, p.1325–1329, (2009)

PET imaging and biodistribution analysis of the effects of succinylated gelatin combined with L-lysine on renal uptake and retention of 64Cu-cyclam-RAFT-c(-RGDfK-)4in vivo., Jin, Zhao-hui, Furukawa Takako, Sogawa Chizuru, Claron Michael, Aung Winn, Tsuji Atsushi B., Wakizaka Hidekatsu, Zhang Ming-Rong, Boturyn Didier, Dumy Pascal, et al. , Eur. J. Pharm. Biopharm., Volume 86, Number 3, p.478–486, (2014)

Oxime-based synthesis of new chromogenic and fluorogenic oligosaccharides., Renaudet, Olivier, and Dumy Pascal , European J. Org. Chem., Number 32, p.5383–5386, (2008)

An oxime-based glycocluster microarray., Hoang, Antoine, Laigre Eugenie, Goyard David, Defrancq Eric, Vinet Francoise, Dumy Pascal, and Renaudet Olivier , Org. Biomol. Chem., Volume 15, Number 24, p.5135–5139, (2017)

Oxime Ligation: A Chemoselective Click-Type Reaction for Accessing Multifunctional Biomolecular Constructs., Ulrich, Sebastien, Boturyn Didier, Marra Alberto, Renaudet Olivier, and Dumy Pascal , Chem. - A Eur. J., Volume 20, Number 1, p.34–41, (2014)

One-pot approach to well-defined biomolecular assemblies by orthogonal chemoselective ligations., Galibert, Mathieu, Dumy Pascal, and Boturyn Didier , Angew. Chemie, Int. Ed., Volume 48, Number 14, p.2576–2579, (2009)

Oligonucleotide Sequential Bis-Conjugation via Click-Oxime and Click-Huisgen Procedures., Meyer, Albert, Spinelli Nicolas, Dumy Pascal, Vasseur Jean-Jacques, Morvan Francois, and Defrancq Eric , J. Org. Chem., Volume 75, Number 11, p.3927–3930, (2010)

Oligonucleotide duplexes with tethered photoreactive ruthenium(II) complexes: influence of the ligands and their linker on the photoinduced electron transfer and crosslinking processes of the two strands., Deroo, Stephanie, Le Gac Stephane, Ghosh Sumana, Villien Mathilde, Gerbaux Pascal, Defrancq Eric, Moucheron Cecile, Dumy Pascal, and De Mesmaeker Andree. Kirsch- , Eur. J. Inorg. Chem., Number 4, p.524–532, (2009)

Novel cyclodecapeptide compounds for use as drugs for diagnosis, prevention, and/or treatment of neurodegenerative diseases., Delangle, Pascale, Pujol Anaies, Dumy Pascal, Renaudet Olivier, and Ferrand Michel. , (2011)

A novel conformationally constrained parallel G quadruplex., Murat, Pierre, Cressend Delphine, Spinelli Nicolas, Van der Heyden Angeline, Labbe Pierre, Dumy Pascal, and Defrancq Eric , ChemBioChem, Volume 9, Number 16, p.2588–2591, (2008)

Noninvasive visualization and quantification of tumor $\alpha$V$\beta$3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4., Jin, Zhao-hui, Furukawa Takako, Galibert Mathieu, Boturyn Didier, Coll Jean-Luc, Fukumura Toshimitsu, Saga Tsuneo, Dumy Pascal, and Fujibayashi Yasuhisa. , Nucl. Med. Biol., Volume 38, Number 4, p.529–540, (2011)

Non-invasive tools for detecting vulnerable atherosclerotic plaques., Fagret, Daniel, Ghezzi Catherine, Dumy Pascal, Riou Laurent, and Boturyn Didier , (2010)

NMR and Theoretical Calculations: A Unified View of the Cis/Trans Isomerization of 2-Substituted Thiazolidine Containing Peptides., Jamet, Hélène, Jourdan Muriel, and Dumy Pascal , J. Phys. Chem. B, Volume 112, Number 32, p.9975–9981, (2008)